Preparation of porous cellulose 3,5-dimethylphenylcarbamate hybrid organosilica particles for chromatographic applications

Abstract

Organic–inorganic hybrids incorporating cellulose tris(3,5-dimethylphenylcarbamate) (CDMPC)-functionalized silica particles can exhibit a high loading capacity with high loadings of the chiral selector.

Carrageenan–Silica Hybrid Nanoparticles Prepared by a Non‐Emulsion Method

“…However, most of the sol–gel‐based methods reported so far are limited to the formation of biopolymer–silica hybrid materials in the form of monoliths,17,18 films,13 fibers,19 or powders without well‐defined particle morphology,16 which may constrain the potential application of these materials. More recently, researchers were successful in tailoring the shape and size of polymer–silica hybrid materials to obtain micro‐ and submicron‐sized particles with spherical morphology by using emulsions 20,21. This achievement has broadened the applications of hybrid silicas as chromatographic materials21 and certainly will have an impact in other applications in which minute size and spherical morphology are relevant such as in drug and gene delivery, and bioimaging 22.…”

“…More recently, researchers were successful in tailoring the shape and size of polymer–silica hybrid materials to obtain micro‐ and submicron‐sized particles with spherical morphology by using emulsions 20,21. This achievement has broadened the applications of hybrid silicas as chromatographic materials21 and certainly will have an impact in other applications in which minute size and spherical morphology are relevant such as in drug and gene delivery, and bioimaging 22. However, emulsion methods require the use of surfactants that need to be eliminated from the final particles.…”

Cellulose type chiral stationary phase based on reduced graphene oxide@silica gel for the enantiomer separation of chiral compounds

“…Zhu et al found that the optical enantiomers of five novel tetrahedral isomeric clusters were directly resolved on a cellulose tris‐(3, 5‐dimethylphenylcarbamate) CSP . Weng et al used a sol‐gel method to obtain organic‐inorganic hybrids of cellulose (3, 5‐dimethylphenylcarbamate) functionalized silica particles, which achieved baseline separation of racemic 2, 2, 2‐trifluoro‐1‐ (9‐anthryl) ethanol …”

Nanocellulose 3, 5‐Dimethylphenylcarbamate Derivative Coated Chiral Stationary Phase: Preparation and Enantioseparation Performance

“…For example, organic-inorganic hybrid materials have been utilized as promising HPLC packing materials to separate racemates. [14][15][16] In addition, a series of dynamic helical poly (phenylacetylene) derivatives as new CSPs were also reported.17 Therefore, the development of novel CSPs is still a research hotspot of new types of chiral separation materials and continues to attract researchers' attention.Nanocrystalline cellulose (NCC) is generated from microcrystalline cellulose (MCC). With the development of NCC, the application fields of cellulose have been extended to sustainable materials, nanocomposites, as well as medical and life sciences.…”

“…For example, organic-inorganic hybrid materials have been utilized as promising HPLC packing materials to separate racemates. [14][15][16] In addition, a series of dynamic helical poly (phenylacetylene) derivatives as new CSPs were also reported. 17 Therefore, the development of novel CSPs is still a research hotspot of new types of chiral separation materials and continues to attract researchers' attention.…”