Preparation of Multicore Colloidosomes: Nanoparticle-Assembled Capsules with Adjustable Size, Internal Structure, and Functionalities for Oil Encapsulation

Abstract

Colloidosomes, also known as Pickering emulsion capsules, have attracted attention for encapsulation of hydrophilic and hydrophobic actives. However, current preparation methods are limited to single core structures and require the use of modified/engineered nanoparticles for forming the shell. Here, we report a fast, simple, and versatile method for producing multi-oil core silica colloidosomes via salt-driven assembly of purely hydrophilic commercial nanoparticles dispersed within an Oil-In-Water-In-Oil (O/W/O) double emulsion template. The internal structure and overall diameter of the capsules can be adjusted by altering the primary and secondary emulsification conditions. With this approach, 7 to 35 µm diameter multicore colloidosomes containing 0.9 to 4.2 µm large oil cores were produced. The capsules can easily be functionalized depending on the type of nanoparticles used in the preparation process. Here, metal oxide nanoparticles, such as Fe3O4, TiO2 and ZnO, were successfully incorporated within the structure, conferring specific functional properties (i.e. magnetism, photocatalysis) to the final microcapsules. These capsules can also be ruptured using ultrasound, enabling easy access to the internal core environments. Therefore, we believe this work offers a promising approach for producing multicore colloidosomes with adjustable structure and functionalities for the encapsulation of hydrophobic actives.

Using Nanotechnology for Enhancing the Shelf Life of Fruits

“…Colloidosomes also called Pickering emulsion capsules, have gained a lot of attention for the Encapsulation of hydrophilic and hydrophobic activities [15]. These are microcapsules whose shell comprises tightly packed colloidal particles.…”