Preparation of High Flexible Composite Film of Hydroxyapatite and Chitosan

Kim, Seong Hoon; Lim, Byoung-Ki; Sun, Fangfang; Koh, Kwangnak; Ryu, Sie Jeong; Kim, Hong-Sung; Lee, Jaebeom

doi:10.1007/s00289-008-1008-5

Cited by 25 publications

(13 citation statements)

References 28 publications

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“…The great advantage of this method is easy preparation and operation without the need of special equipment [14,16]. The prepared film often exhibits high flexibility [16].…”

Section: Solvent/solution Casting Methodsmentioning

confidence: 99%

“…The final dispersion is casted in to predefined mold or thin films are prepared and at the end the solvent was allowed to evaporate [14,15]. The great advantage of this method is easy preparation and operation without the need of special equipment [14,16]. The prepared film often exhibits high flexibility [16].…”

Section: Solvent/solution Casting Methodsmentioning

confidence: 99%

“…The great advantage of this method is easy preparation and operation without the need of special equipment [14,16]. The prepared film often exhibits high flexibility [16].The advantages of this method are: good dispersion of the filler in the polymer matrix and removal of solvent from final nanocomposite. Combination of solvent casting with another method should solve several problems.…”

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confidence: 99%

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Preparation and Mechanical Properties of Polymeric Nanocomposites with Hydroxyapatite and Hydroxyapatite/Clay Mineral Fillers - Review

Martynková¹

2015

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Polymer-ceramic nanocomposites are hybrid organo-inorganic materials. The filler phase is required at nanometer level, it means that at least one dimension of the filler phase is less than 100 nm. Boosted research interest in field of the nanocomposites is observed last decade [1][2][3][4] because of remarkable improvement of various nanocomposite properties adding low volume fractions of fillers [3]. The virgin polymer exhibits poor mechanical properties such as low strength and modulus. Introducing a small amount of ceramic particles into the polymer matrix, we can observe improvement of the properties of polymer [4]. One of the most common filler for polymers, especially for medical uses is hydroxyapatite, which is the most common apatitic calcium phosphate ceramic. The most important calcium phosphates are hydroxyapatite, tricalcium phosphate and dicalcium phosphate. Hydroxyapatite (HAp), Ca 10(PO4)6(OH)2, is a major component of hard tissues. HAp is very cheap material, which has wide utilization in medical field and also in industry. Synthetic HAp finds many applications mainly in bioceramic [5][6][7][8].Clay minerals are natural materials from phyllosilicate family. They are hydrous aluminium, iron and magnesium silicates with layered structure. Clays have characteristic layered structure contains aluminia octahedral layer and two silica tetrahedral sheets [9]. Polymer/HAp nanocomposite is widely studied materials in recent years. The main advantage is their utilization in medicine, due to improved mechanical properties and also biocompatible properties [10]. The aim of this mini review is to summarize the preparation of polymer/HAp nanocomposites, the influence of HAp filler on mechanical properties of nanocomposite and also the dispersion of hydroxypapatite in polymeric matrix. Polymer/clay mineral composites are widely used in recent years, and also the exploration of this topic is significant. It was many times proven that addition of small amount of clay mineral in to the polymer matrix improves the mechanical properties of polymer [11][12][13].Combination of polymer, hydroxyapatite and clay mineral leads to the composite with unique properties and wide range of application, especially in the medicine, since the non-living, inorganic chemical make-up of our teeth and bones is primarily composed of hydroxyapatite (Figure1).In this review the main aspects of apatitic calcium phosphates are presented. Focus is here on basic preparation techniques and their limitation, properties of prepared nanocomposites and draft-possibilities of application. Martynková GS, et al., J Nanotechnol Nanomed Nanobiotechnol 2015, 2: 007 DOI: 10.24966/NTMB-2044 HSOA Journal of Nanotechnology: Nanomedicine & Nanobiotechnology Review Article AbstractNanocomposites of hydroxyapatite/polymer and hydroxyapatite/ polymer/clay mineral are studied for pronounced further application in medicine. The ceramic filler influence the mechanical properties of polymeric matrix. This mini review summarizes the influence of hydroxyapatite on...

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“…The great advantage of this method is easy preparation and operation without the need of special equipment [14,16]. The prepared film often exhibits high flexibility [16].…”

Section: Solvent/solution Casting Methodsmentioning

confidence: 99%

Section: Solvent/solution Casting Methodsmentioning

confidence: 99%

mentioning

confidence: 99%

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Preparation and Mechanical Properties of Polymeric Nanocomposites with Hydroxyapatite and Hydroxyapatite/Clay Mineral Fillers - Review

Martynková¹

2015

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“…As barreiras utilizadas devem ser biocompatíveis (não devem provocar rejeição in vivo) e não permeáveis a células, pois elas devem criar e manter um espaço no interior da lesão, de modo que permita crescimento de tecido ósseo em detrimento ao crescimento de tecido epitelial e conjuntivo. Além disso, devem selar totalmente o local, impedindo acúmulo de bactérias no interior da região em tratamento (LAURELL;GOTTLOW, 1998;ZHANG et al, 2013). Suas propriedades físico-químicas e mecânicas também devem ser levadas em consideração (BOTTINO et al, 2012), pois as barreiras não devem colapsar durante o tratamento.…”

Section: Regeneração Tecidual Guiada (Rtg)unclassified

“…Adicionalmente, a HA possui uma grande similaridade com as apatitas biológicas com relação à sua estequiometria e cristalinidade, características que a tornam ainda mais reativas no meio biológico, a textura suave do compósito evita danos aos tecidos moles próximos ao implante(GINEBRA, 2006).Estas características atraíram o interesse na preparação de compósitos de QS/HA para seu uso em ortopedia e engenharia de tecidos. Tais compósitos são preparados por variados métodos, gerando produtos com diferentes formas, como por exemplo, filmes(KIM et al, 2008), membranas (TENG et al, 2008, esferas Eles também demonstraram os dois tipos de interações queocorrem entre a QS e nano-HA, reproduzidas na Figura 10. A Figura 10 (a) mostra as ligações de hidrogênio entre a QS com as hidroxilas da HA.…”

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Avaliação das características físico-químicas e citotóxicas de membranas de gelatina/quitosana com hidroxiapatita obtidas por precipitação <i>in situ</i>

Habitzreuter¹

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Bioinspired Hydroxyapatite/Poly(methyl methacrylate) Composite with a Nacre‐Mimetic Architecture by a Bidirectional Freezing Method

et al. 2015

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Using a bidirectional freezing technique, combined with uniaxial pressing and in situ polymerization, "nacre-mimetic" hydroxyapatite/poly(methyl methacrylate) (PMMA) composites are developed by processing large-scale aligned lamellar ceramic scaffolds. Structural and mechanical characterization shows "brick-and-mortar" structures, akin to nacre, with interesting combinations of strength, stiffness, and work of fracture, which provide a pathway to making strong and tough lightweight materials.

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Preparation of High Flexible Composite Film of Hydroxyapatite and Chitosan

Cited by 25 publications

References 28 publications

Preparation and Mechanical Properties of Polymeric Nanocomposites with Hydroxyapatite and Hydroxyapatite/Clay Mineral Fillers - Review

Preparation and Mechanical Properties of Polymeric Nanocomposites with Hydroxyapatite and Hydroxyapatite/Clay Mineral Fillers - Review

Avaliação das características físico-químicas e citotóxicas de membranas de gelatina/quitosana com hidroxiapatita obtidas por precipitação <i>in situ</i>

Bioinspired Hydroxyapatite/Poly(methyl methacrylate) Composite with a Nacre‐Mimetic Architecture by a Bidirectional Freezing Method

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