Preparation of Electrospun Polyvinyl Alcohol/Nanocellulose Composite Film and Evaluation of Its Biomedical Performance

Abstract

Using polyvinyl alcohol (PVA) and nanocellulose (NC) as raw materials, PVA/NC nanofiber membranes were prepared by electrospinning. The hydrogen bonding, crystalline properties and microscopic appearance of PVA/NC membranes with different NC contents were characterized. The mechanical properties, liquid absorption and cytotoxicity of the nanofiber membrane were evaluated. The results show that the free hydroxyl group of the PVA/NC nanofiber membranes have a maximum value of 9% at a mass fraction of 6% NC. The crystallinity of the PVA/NC nanofiber membranes and the average diameter of the nanofibers decreased and then increased as the NC content increased, with a minimum value of 38.23% and 272.03 nm, respectively, at 6% NC content. At this time, the contact angle was the smallest. The maximum strength of the PVA/NC nanofiber membranes is 75.8% higher than that of the PVA membrane at 2% NC content. With increasing NC content, the absorption of water, PBS sustained-release suspensions and artificial blood by PVA/NC nanofiber membranes increases. Cytotoxicity tests have shown that PVA/NC nanofiber membranes are non-toxic, have good cytocompatibility and are expected to be used in the field of medical dressings.

Phosphorylated Curdlan Gel/Polyvinyl Alcohol Electrospun Nanofibres Loaded with Clove Oil with Antibacterial Activity

“…Natural biopolymers such as polysaccharides and their derivatives (alginates, chitosan, cellulose, curdlan, etc. ), proteins (collagen, gelatine, fibrin, keratin) and proteoglycans are used for wound dressings preparation due to their biodegradability, biocompatibility, haemostatic activity, and non-toxicity [ 8 , 9 , 10 ]. We chose curdlan because it is a natural polysaccharide with a higher potential in biomaterials fabrication.…”

Lignocellulosic full-components hydrogelation using steam-exploded corn stover

“…This may be due to the addition of CS and SECS leading to hydrogen bonding interactions with PVA, resulting in a decrease in the orderliness of its crystal structure. 24 Fourier-transform infrared spectroscopy (FTIR) was employed to assess the cross-linking status of the components in the hydrogel samples. The intensity of the peaks linked to hydroxyl groups around 3300 cm −1 in the SECS-PVA hydrogel was significantly higher compared to that in other samples (Fig.…”

“…This may be due to the addition of CS and SECS leading to hydrogen bonding interactions with PVA, resulting in a decrease in the orderliness of its crystal structure. 24…”

Electrospun Filtering Membrane Designed as Component of Self-Decontaminating Protective Masks

“…Some studies have shown that adding nanocellulose particles can result in a crystalline structure. The PVA matrix and the cellulose nanowhiskers form a strong hydrogen bond interaction [ 51 , 52 ].…”