Preparation of DNA-functionalized surfaces for simultaneous homeotropic orientation of liquid crystals and optical recognition of analytes: application to the determination of progesterone

A Label-Free Liquid Crystal Biosensor Based on Specific DNA Aptamer Probes for Sensitive Detection of Amoxicillin Antibiotic

“…The upper and bottom glass slides were prepared following previous studies [ 27 , 28 ]. The LC cells were fabricated as previously described [ 33 , 34 ]. The details are provided in the Supplementary Materials .…”

“…They possess distinctive properties, such as ease of synthesis, high affinity, high specificity and stability, cost-effectiveness, and wide applicability [ 25 , 29 , 31 ]. Thus, LC-based aptasensors have been applied for the determination of various analytes, including sulfadimethoxine [ 18 ], pesticides [ 24 ], polychlorinated biphenyls [ 29 ], ractopamine [ 32 ], hormones [ 33 ], proteins [ 22 , 28 , 34 ], antibiotics [ 23 , 35 ], and heavy metal ions [ 25 , 26 , 36 , 37 ].…”

A homogeneous label-free electrochemical aptasensor based on an omega-like DNA nanostructure for progesterone detection

“…Artificial enzyme mimics, particularly DNAzymes, have been used as signal tags in biosensing strategies. 24 Recent research has shown that, via powerful π–π interactions with peroxidase-like activity in the presence of H 2 O 2 , hemin can extrinsically stack on some G-quadruplex DNA aptamers to form a more stable hemin/G-quadruplex structure. 25,26 However, the aptamer molecule is relatively small, with a structure more flexible than that of the protein, making it more susceptible to structural changes.…”