Preparation of cypress (Cupressus sempervirens L.) essential oil loaded poly(lactic acid) nanofibers

Abstract

This study investigated the production of poly(lactic acid) (PLA) nanofibers containing cypress (CUP) essential oil (EO) via electrospinning. The nanofibers were produced from polymer solution prepared with different percentages of cypress EO. Cypress EO-containing PLA nanofibers were characterized and some mechanical and thermal properties were examined using thermogravimetric analysis, scanning electron microscopy, Fourier-transform infrared spectroscopy, and dynamic mechanical analysis. The thermal stability of the nanofibers was reduced depending on the percentage of the cypress EO. As the ratio of the cypress EO to polymer matrices was increased, it was observed that the glassy transition temperatures of the nanofibers decreased and their flexibility increased. The T g value was determined to be 53.74°C for the neat PLA nanofiber, while 51.83°C for the PLA-CUP nanofiber (containing 15% cypress EO). According to the results of releasing trial, the increased amount of cypress EO resulted in less cypress EO releasing from polymer matrices. The nanofibers were observed to exhibit antibacterial activity against Escherichia coli and Staphylococcus aureus. The inhibition zone diameter of the nanofibers containing 10% cypress EO was 20 mm for S. aureus and 16 mm for E. coli, while 10 mm in the presence of Kanamycin.

Preparation and characterization of poly(lactic acid) (PLA) based poly(ethylene glycol)/eugenia caryophyllus essential oil added smart composite nanofibers for biothermal stabilization

“…Thermal degradation of PLA and pure PLA nano bres was determined with a thermogravimetric analyzer (SDT Q600 V20.9 Build 20 ) between 0-650 ºC under a nitrogen atmosphere at a heating rate of 10°C min − 1 [20,22].…”

“…On the other hand, when PLA-based nanomaterials form composites with antibiotic compounds by electrospinning method, they can produce controlled release [19]. The oscillation of nano bers when loaded with essential oil has been observed in Cupressus sempervirens L. loaded nano ber study and it is thought that it can make an important contribution to drug designs [20].…”

Preparation and Characterization of Polylactic Acid Based Nanofiber Loaded with Tangerine Peel (Citrus Unshiu) Essential Oil

“…Thermal degradation graphs of PLA/TPEO nanofibers were determined with a thermogravimetric analyzer (SDT Q600 V20.9 Build 20) under nitrogen atmosphere at a heating rate of 10 °C min -1 and between 0-700 °C [24].…”

An In Vitro Study of Antibacterial Properties of Electrospun Hypericum perforatum Oil-Loaded Poly(lactic Acid) Nonwovens for Potential Biomedical Applications

“…Researchers have been worked about the development antibacterial PLA-based electrospun materials using chitosan and silver [43], thymol [44], propolis [45], silver and vitamin E [46], copaiba (Copaifera sp.) oil [47], tetracycline hydrochloride and chitosan [48], cinnamon essential oil [49], thymoquinone [50], tea tree and manuka oil [51], carvacrol [52], clary sage and black pepper [53], terpinen-4-ol [54], epidermal growth factor [55], quercetin [56], Nigella sativa herbal extract [57], Eucalyptus essential oil [58], silver diclofenac complex [59], chitosan, black pepper essential oil and limonene [60], selenium and clarithromycin [61], cefazolin [62], silver nanoparticles [63], zinc oxide [64], thyme essential oil [65], zenian (Carum copticum) essential oil [66], birch bark triterpene extract [67], Capparis spinosa L. extracts [68], Plumbago europaea plant extract [69], curcumin [70], babassu oil [71], and cypress (Cupressus sempervirens L.) essential oil [72].…”