Preparation of Chitin-graphene Eco-friendly Dressing and Its Effect on Wound Healing

Abstract

The aim of this paper is to prepare the Chitin-graphene eco-friendly dressing, and also divided into four groups. Group Control was Chitin and Group A was Chitin+dopamine glue, respectively, at 0.2ug/ml, 1ug/ml, 5ug/ml (Namely group B, C and D). The precipitation of the adherent composite ions could be found under 5*103 times microscopy in group D. the contact angle test showed that the material was hydrophilic. The drug loading rate in group BCD was 30-40 (ug:mg), and entrapment efficiency was 70%-80%.there was no difference between groups (P>0.05).the cumulative release percentages were 86.7%, 88.4% and 89.6% after 72h in group B,C and D, respectively. After 7 days of injury, the wound healing rate was D > C > B > A > Control (P < 0.05), and the length of neonatal epithelium also showed the same trend.