Preparation of calcium–phosphate bioceramics from natural resources

Balázsi, Csaba; Wéber, Ferenc; Kövér, Zsuzsanna; Horváth, Edina; Németh, Csaba

doi:10.1016/j.jeurceramsoc.2006.04.016

Cited by 165 publications

(89 citation statements)

References 10 publications

(8 reference statements)

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“…It also releases calcium and phosphate ions, and it leads to osteoinduction. Hydroxyapatites are inorganic materials and based on their properties that are widely used in tissue engineering and bone replacement, it is also used as a coating for fixing prostheses [53,54]. Hydroxyapatite has been used clinically in a wide range of forms and applications.…”

Section: 2mentioning

confidence: 99%

“…Several methods have been developed in producing hydroxyapatite directly from corals but two of such processes are widely utilized and reported. These techniques are hydrothermal and microwave processes, although others such as sol-gel coating are also in use among others [53].…”

Section: 3mentioning

confidence: 99%

“…An investigation showed that calcium phosphate-based bioceramics have been synthesized by using eggshell-derived raw materials and phosphoric acid at different mixing ratios. The mineral composition of cockle shell is almost similar to that of coral and it was suggested that cockle shell has the potential to be used as a material for orthopaedic applications [53,65].…”

Section: Shellmentioning

confidence: 99%

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Natural Products: A Minefield of Biomaterials

Ige

Umoru

Aribo

2012

ISRN Materials Science

152

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The development of natural biomaterials is not regarded as a new area of science, but has existed for centuries. The use of natural products as a biomaterial is currently undergoing a renaissance in the biomedical field. The major limitations of natural biomaterials are due to the immunogenic response that can occur following implantation and the lot-to-lot variability in molecular structure associated with animal sourcing. The chemical stability and biocompatibility of natural products in the body greatly accounts for their utilization in recent times. The paper succinctly defines biomaterials in terms of natural products and also that natural products as materials in biomedical fields are considerably versatile and promising. The various types of natural products and forms of biomaterials are highlighted. Three main areas of applications of natural products as materials in medicine are described, namely, wound management products, drug delivery systems, and tissue engineering. This paper presents a brief history of natural products as biomaterials, various types of natural biomaterials, properties, demand and economic importance, and the area of application of natural biomaterials in recent times.

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Section: 2mentioning

confidence: 99%

Section: 3mentioning

confidence: 99%

Section: Shellmentioning

confidence: 99%

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Natural Products: A Minefield of Biomaterials

Ige

Umoru

Aribo

2012

ISRN Materials Science

152

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“…Commercialization of the dental and surgical applications of calcium orthophosphate (mainly, HA) bioceramics occurred in the 1980's, largely due to the pioneering efforts by Jarcho [80][81][82][83] in the USA, de Groot [84][85][86] in Europe and Aoki [87][88][89][90][91][92][93][94][95][96][97][98][99][100][101][102][103] in Japan. Shortly afterwards HA has become a bioceramic of reference in the field of calcium orthophosphates for biomedical applications.…”

Section: Historymentioning

confidence: 99%

“…Although calcium orthophosphate bioceramics currently can be prepared from various sources [96][97][98][99][100][101][102][103][104][105][106][107][108][109]787], up to now, all attempts to synthesize bone replacement materials for clinical applications featuring the physiological tolerance, biocompatibility and a longterm stability have had only a relative success. This shows the superiority and a complexity of the natural structures [110].…”

Section: Chemical Composition and Preparationmentioning

confidence: 99%

Untitled

2011

BIO

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In the late 1960's, a strong interest was raised in biomedical applications of ceramic materials (named bioceramics a little bit later). Bioceramics was initially used as reasonable alternatives to metals in order to increase their biocompatibility. However, within a short period, it has grown into a diverse class of biomaterials, presently including three essential types: relatively bioinert, bioactive (or surface reactive) and bioresorbable bioceramics. This review is limited to bioceramics prepared from calcium orthophosphates only, which belong to the categories of bioactive and bioresorbable compounds. There have been a number of important advances in this field during the past 30 -40 years. The research was shifted from an initial study on the develop-ment of bioinert bioceramics towards bioactive and bioresorbable bioceramics, and these different types of calcium orthophosphate bioceramics can be tuned through the structural and compositional control. At the turn of the millennium, a new concept of calcium orthophosphate bioceramics has been developed to promote a regeneration of bones. Current biomedical applications of calcium orthophosphate bioceramics include artificial replacements for hips, knees, teeth, tendons and ligaments, as well as repair for periodontal disease, maxillofacial reconstruction, augmenttation and stabilization of the jawbone, spinal fusion and bone fillers after tumor surgery. Potential future applications of calcium orthophosphate bioceramics are demonstrated in drug delivery systems, effective carriers of growth factors, bioactive peptides and/or various types of cells for tissue engineering purposes.

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