Preparation of an optimum mobile phase for the simultaneous determination of neurochemicals in mouse brain tissues by high-performance liquid chromatography with electrochemical detection

Determination of monoamine transmitters and tyrosine in biological samples by capillary electrophoresis with electrochemical detection

“…The assay results are summarized in Table I. The contents of MAs and Tyr in the investigated biological samples are similar to those in previous reports [13,14]. L -l perchloric acid, respectively.…”

“…Several methods have been developed for the determination of one or more MAs in biological samples, such as liquid chromatography (LC) with fluorometric [11,12] or electrochemical detection [13][14][15][16][17], ultra-microelectrode [18,19] and gas chromatography coupled with mass spectrometry (GC-MS) [20,21]. CE has also become an attractive technique for the determination of MAs owing to its high resolution [22][23][24][25][26].…”

Application of ionic liquid for extraction and separation of bioactive compounds from plants

“…Adrenergic amines, such as octopamine (Octo), synephrine (Syne) and tyramine (Tyra), are the major active compounds in these herbs [127]. The separation and quantification of adrenergic amines in different samples, such as mouse central nerves and C. aurantium crude drugs, by HPLC with an electrochemical detector or UV detector have been reported [128][129][130][131][132][133][134]. These amine compounds, however, can interact strongly with the free silanols on the surface of the stationary phase.…”

High‐performance liquid chromatography methods for the analysis of adrenergic amines and flavanones in Citrus aurantium L. var. amara

“…Several HPLC methods with electrochemical detection have been described for the separation and quantification of biogenic amines in different matrices, such as in the mouse central nervous system (Downer and Martin, 1987;Nagao and Tanimura, 1988;Leung and Tsao, 1992) and in crude drugs prepared from C. aurantium (Kusu et al, 1992). However, adrenergic amines have not been quantified in C. aurantium dry extracts or herbal medicines.…”