Preparation of an acryloyl β‐cyclodextrin‐silica hybrid monolithic column and its application in pipette tip solid‐phase extraction and HPLC analysis of methyl parathion and fenthion

Abstract

An acryloyl β-cyclodextrin-silica hybrid monolithic column for pipette tip solid-phase extraction and high-performance liquid chromatography determination of methyl parathion and fenthion has been prepared through a sol-gel polymerization method. The synthesis conditions, including the volume of cross-linker and the ratio of inorganic solution to organic solution, were optimized. The prepared monolithic column was characterized by thermogravimetric analysis, scanning electron microscopy, and Fourier transform infrared spectroscopy. The eluent type, volume and flow rate, sample volume, flow rate, acidity, and ionic strength were optimized in detail. Under the optimized conditions, a simple and sensitive pipette tip solid-phase extraction with high-performance liquid chromatography method was developed for the determination of methyl parathion and fenthion in lettuce. The method yielded a linear calibration curve in the concentration ranges of 15-400 μg/kg for methyl parathion and 20-400 μg/kg for fenthion with correlation coefficients of above 0.9957. The limits of detection were 4.5 μg/kg for methyl parathion and 6.0 μg/kg for fenthion, respectively. The recoveries of methyl parathion and fenthion spiked in lettuce ranged from 96.0 to 104.2% with relative standard deviations less than 8.4%.

Ratiometric Fluorescent Sensor Based on Hydrogen-Bond Triggering the Internal Filter Effect for Enzyme-Free and Visual Monitoring Pesticide Residues

“…But frequent pesticide applications could contaminate the environment and enter the food chain, leading to acute or chronic poisoning. , Therefore, it is very important to find cheap, fast, highly selective, and sensitive detection methods to monitor these substances for tracking pesticide residues in the environment. Many well-established methods have been widely reported for detecting MP residues, such as electrochemical, − fluorescence, − gas chromatography (GC), − spectrophotometry, − and immunoassay. − Although the aforementioned methods have outstanding sensitivity and accuracy, their use is still constrained by some inherent limitations, such as complicated preprocessing, high cost, and operational proficiency, which prevents their use in real-time situations.…”

Chiral covalent organic framework incorporated organic polymer monolithic capillary column for enantioseparations

“…Usually, one-step chiral in-situ polymerization is employed to prepare chiral MCCs. The commonly used chiral stationary phases in MCCs are various derivatives of β-cyclodextrin [25][26][27][28], and others include cellulose [29][30][31], pepsin [32,33], polymyxin-B [34] and (S)-(-)−1-(2-naphthyl)ethylamine [35]. It is worth mentioning that metal-organic frameworks [29,32], COFs [30], and gold nanoparticles [36] can improve the enantioseparation ability of chiral MCCs.…”

Self‐assembly preparation of Zn2+‐immobilized silica hybrid monolith and application in solid‐phase micro‐extraction of β‐agonists

“…Silica-based monoliths as a medium of SPME are confirmed to be superior including thermal stability, mechanical strength, uniform structure, controllable morphology, convective mass transfer, and porous structure [2,3]. For specified analyte detection, various functional groups are introduced into silica monoliths to modulate the extraction performances [4][5][6]. For example, octyl-functionalized silica hybrid monoliths are used in SPME procedures in the determination of cannabidiol and tetrahydrocannabinol [7].…”