Preparation of amidated derivatives of carboxymethylcellulose

Biocompatible nanocarriers for passive transdermal delivery of insulin based on self-adjusting N-alkylamidated carboxymethyl cellulose polysaccharides

“…The peaks of the original CMC were found to be in accordance with those reported in previous publications. 54 The new appearing peaks of the modified CMC-6 or CMC-12, correlate with FTIR 55,56 and 1 H-NMR 35,56 data of previously reported modified polysaccharides. Both characterizations methods verify the formation of new secondary amide bonds confirming N-alkylamide CMC modifications.…”

An investigation on the adsorption and removal performance of a carboxymethylcellulose-based 4-aminophenazone@MWCNT nanocomposite against crystal violet and brilliant green dyes

“…Esters are commonly produced by suspending H-CMC in an alcohol reagent combination to alter the equilibrium of the reaction and prevent intermolecular interactions between CMC chains. [29][30][31] A new nanocomposite material has also been fabricated using a CMC amide derivative (A-PH/CMC) in the presence of MWCNTs. The fabricated material was additionally investigated against the adsorption and removal performance of crystal violet and brilliant green dyes from aqueous solutions.…”

Solvent-Free Synthesis of Amidated Carboxymethyl Cellulose Derivatives: Effect on the Thermal Properties

“…Nevertheless, the lack of solubility of CMC in organic solvents, under both its sodium salt (NaCMC) and acid (HCMC) form, significantly limits its derivatization by grafting of hydrophobic molecules. Currently, only few strategies allow for the covalent grafting of hydrophobic moieties onto CMC, involving either the dispersion of the polysaccharide in organic solvent [11,12,13,14,15,16,17,18] or its previous modification (i.e., ion exchange to obtain the tetrabutylammonium (TBA) salt) [19,20,21] to form an organo-soluble derivative. Another possibility is represented by the condensation of CMC with an amine, at high temperature and in heterogeneous conditions, which results in the elimination of water and formation of an amide bond [22,23].…”