Preparation of Alkyl Chlorophosphines

Steric Control in the Synthesis of Phosphinous Acid-Coordinated Mono- and Binuclear Platinum(II) Complexes

“…Secondary phosphine oxides are valuable intermediates in phosphorus chemistry, especially used as precursors of tertiary phosphine oxides . Several preparative methods of symmetrically substituted SPOs have been developed; for instance, hydrolysis of R 2 PY (Y = Cl or NR′ 2 ), addition of Grignard reagents to dialkylphosphites, reduction of phosphoryl chlorides, ,, oxidation of secondary phosphines, or reductive cleavage of tertiary phosphine oxides are among the most relevant methods. Most of the syntheses have been described in homogeneous media , and involved multistep routes.…”

Iron(0) and ruthenium(0) complexes with tridentate phosphonite ligands and their potential for ketene formation from methyl iodide, CO and a base

“…The conversion of the P-Cl bonds in chlorophosphine derivatives appears to have a wider scope than the alcoholysis of aminophosphines [20]. Approaches involving bis(primaryphosphine) derivatives of the type RP[CH 2 CH 2 CH 2 PH 2 ] 2 , where the P-H bonds can be converted to P-Cl bonds by a variety of methods [21][22][23][24][25][26] are restricted by the reactivity of the internal tertiary phosphine function, which readily quaternizes in the presence of P-Cl bonds. Protecting groups such as BH 3 or sulfur cannot be envisaged because of the alcoholysis conditions (tertiary amine base are typically used to deprotect phosphine borane adducts) [27][28][29] or the desulfuration conditions, respectively.…”

“…J PP = 51 Hz, -P(C 6 H 11 )), 192.2 (d, 2 J PP = 51 Hz, -P[OCH(CH 3 ) 2 ] 2 ).13 C{ 1 H} NMR (C 6 D 6 , 298 K): 20.1 (m, -CH 2 CH 2 CH 2 -),24.5 (m, -CH(CH 3 ) 2 ), 26.6 (dt, J CP = 4.3, 21 Hz, -CH 2 CH 2 CH 2 -P(C 6 H 11 )), 27 (s, Cyclohexyl C para), 28.1 (d,3 J CP = 11.3 Hz, Cyclohexyl C meta), 29.7 (d, 2 J CP = 12,1 Hz, Cyclohexyl C ortho), OCH(CH 3 ) 2 ] 2 ), 38.4 (d, 1 J CP = 14 Hz, Cyclohexyl C ipso), 69.2 (m, -P[OCH(CH 3 ) 2 ] 2 ), 215.4 (br, CO)). IR (CD 2 Cl 2 , cm À1 ): m CO 1842 (s) and 1901 (s).…”

Organische Phosphorverbindungen 40. Methoden zur Herstellung von Pentamethylen‐1,5‐bis‐(dihydroxyphosphonylmethyl‐phosphinsäure) [1]

“…bei Zimmertemperatur, herzustellen, ,misslang, trotzdem diese Methode bei der Herstellung von CCl,P(OEt), [6] und ClCH,P(OCH,), [7] erfolgreich gewesen war. Erst als wir die Veresterung von Chlormethyl-dichlorphosphin bei 0" bis -10" ausfiihrten, konnten die Chlormethylphosphonite I und I1 in niedriger Ausbeute isoliert werden.…”