Preparation of AAEK-functionalized cellulose film with antibacterial and anti-adhesion activities

Zhou, Zongbao; Wang, Lei; Ying-kui, HU; Song, Rijian; Mei, Naibin; Chen, Tao; Tang, Shunqing

doi:10.1016/j.ijbiomac.2020.11.143

Cited by 8 publications

(3 citation statements)

References 47 publications

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“…Zhou et al reported that ethyl ketones (AAEK) were covalently grafted onto cellulose films (CF) via a copper-catalyzed azide–alkyne 1,3-dipolar cycloaddition click reaction. 61 The purpose of this study is to explore the effectiveness of surface-decorated aryl(β-amino) AAEK, a promised enzyme A (SrtA) inhibitor of Staphylococcus aureus , to improve the anti-adhesion ability of biomaterials. Du et al synthesized and grafted AACA onto the surface of PIB by plasma pre-treatment and UV-induced graft polymerization.…”

Section: Covalent Grafting Technology In Surface Modification Processesmentioning

confidence: 99%

Surface modifications of biomaterials in different applied fields

Wang

2023

RSC Adv.

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Section: Covalent Grafting Technology In Surface Modification Processesmentioning

confidence: 99%

Surface modifications of biomaterials in different applied fields

Wang

2023

RSC Adv.

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“…The N peak of CNDs@C�C could be fitted as one peak labeled as amide compounds, while the N peaks of CNDs@N 3 were decomposed and fitted as three peaks labeled as N + azide, N azide, and N − azide, respectively. 42 When the CuAAC reaction was finished, the two characteristic peaks disappeared to form a broad peak around 401 eV, which represented the typical peak of 1,2,3-triazole. 42,43 This indicates that the alkynyl and azide have reacted and converted to triazole groups, which provides evidence of the successful covalent cross-linking of the two clickable CNDs.…”

Section: Synthesis and Characterizations Of The W/omentioning

confidence: 99%

“…42 When the CuAAC reaction was finished, the two characteristic peaks disappeared to form a broad peak around 401 eV, which represented the typical peak of 1,2,3-triazole. 42,43 This indicates that the alkynyl and azide have reacted and converted to triazole groups, which provides evidence of the successful covalent cross-linking of the two clickable CNDs. In addition, zeta potentials of the CNDs, CNDs@C�C, CNDs@N 3 , and W/O assembly were also examined and are displayed in Figure S6a.…”

Section: Synthesis and Characterizations Of The W/omentioning

confidence: 99%

Covalent Assembly of Clickable Carbon Nanodots in Water-in-Oil Emulsion for Enhanced Antibacterial Photothermal Therapy

Wang

Zhang

et al. 2022

ACS Appl. Nano Mater.

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One challenge in the field of photothermal therapy (PTT) is to design an assembly of carbon nanodots (CNDs) with enhanced light absorption in the near-infrared (NIR) spectral region and improved photothermal conversion efficiency. Herein, a type of CND assembly was fabricated using a covalent click reaction in a water-in-oil emulsion system (abbreviated as W/O assembly), providing excellent stability, controllable size distributions, enhanced NIR absorption, and improved applications in photothermal imaging (PTI), photoacoustic imaging (PAI), and PTT. A mechanism based on energy dissipation was proposed in detail to explain the changes in photophysical properties before and after CND assembly. In addition, an outstanding antibacterial effect was also observed during the in vitro phototherapy of drug-resistant pathogens. Importantly, the results of in vivo infection assays further verified satisfying photokilling effect toward drug-resistant bacteria and excellent biosafety to normal cells and tissues. Given the benefits of the covalent CND assembly developed in this work, it might have potential applications in the following aspects: (1) strategy of the controllable covalent assembly could be extended to other nanosystems and (2) in situ CND assembly could be built at disease sites based on microenvironment-triggered bioorthogonal click reactions, improving targeting performance and reducing the side effects of PTT.

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