Preparation of a teicoplanin-bonded chiral stationary phase for simultaneous determination of clenbuterol and salbutamol enantiomers in meat by LC-MS/MS

Li, Liang; Li, Laisheng; Jin, Yifeng; Shuang, Yazhou; Wang, Hui

doi:10.1016/j.microc.2020.104925

Cited by 12 publications

(5 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Chiral columns based on teicoplanin, vancomycin, and teicoplanin aglycone using superficially porous (core-shell) particles as CSPs have become commercially available, namely, TeicoShell, Van-coShell, and TagShell, respectively. Besides, the preparation of macrocyclic antibiotic-based CSPs through different bonding strategies has also been studied in recent years [88,89]. Cong and co-workers prepared a vancomycinbased CSP using photochemistry [88].…”

Section: Macrocyclic Antibiotic-based Cspsmentioning

confidence: 99%

“…This method is green and effective and the CSP exhibited superior chiral resolution of a variety of chiral compounds. Li et al reported a new preparation of teicoplanin-bonded CSP using the "thiol-ene" click reaction [89]. Additionally, some recent applications of macrocyclic antibiotic-based CSPs have also been reported [90][91][92].…”

Section: Macrocyclic Antibiotic-based Cspsmentioning

confidence: 99%

See 1 more Smart Citation

Recent progress in the development of chiral stationary phases for high‐performance liquid chromatography

Zhang

2021

J of Separation Science

View full text Add to dashboard Cite

Separations and analyses of chiral compounds are important in many fields, including pharmaceutical production, preparation of chemical intermediates, and biochemistry. High-performance liquid chromatography using a chiral stationary phase is regarded as one of the most valuable methods for enantiomeric separation and analysis because it is highly efficient, is broadly applicable, and has powerful separation capability. The focus for development of this method is the identification of novel chiral stationary phases with superior recognition performance and good stability. The present article reviews recent progress in the development of new chiral stationary phases for high-performance liquid chromatography between January 2018 and June 2021. These newly reported chiral stationary phases are divided into three categories: small organic moleculebased (cyclodextrin and its derivatives, macrocyclic antibiotics, cinchona alkaloids, and other low molecular weight chiral molecules), macromoleculebased (cellulose and amylose derivatives, chitin and chitosan derivatives, and synthetic helical polymers) and chiral porous material-based (chiral metal-organic frameworks, chiral covalent organic frameworks, and chiral inorganic mesoporous silicas). Each type of chiral stationary phase is discussed in detail.

show abstract

Section: Macrocyclic Antibiotic-based Cspsmentioning

confidence: 99%

Section: Macrocyclic Antibiotic-based Cspsmentioning

confidence: 99%

Recent progress in the development of chiral stationary phases for high‐performance liquid chromatography

Zhang

2021

J of Separation Science

View full text Add to dashboard Cite

show abstract

“…Currently, the detection techniques for LMP residues in animal feed and food include high-performance liquid chromatography (HPLC) [20,21], liquid chromatography-mass spectrometry (LC-MS) [22,23], gas chromatography-mass spectrometry (GC-MS) [24], ultrahigh-performance liquid chromatography (UHPLC) [25], and capillary electrophoresis (CE) [26], etc. Although the above methods have lower limits of detection and better stability, they have the disadvantages of long detection time, expensive instruments, and complicated operation.…”

Section: Introductionmentioning

confidence: 99%

Advance in Detection Technique of Lean Meat Powder Residues in Meat Using SERS: A Review

Guo,

Peng,

Qin

et al. 2023

Molecules

View full text Add to dashboard Cite

Food that contains lean meat powder (LMP) can cause human health issues, such as nausea, headaches, and even death for consumers. Traditional methods for detecting LMP residues in meat are often time-consuming and complex and lack sensitivity. This article provides a review of the research progress on the use of surface–enhanced Raman spectroscopy (SERS) technology for detecting residues of LMP in meat. The review also discusses several applications of SERS technology for detecting residues of LMP in meat, including the enhanced detection of LMP residues in meat based on single metal nanoparticles, combining metal nanoparticles with adsorbent materials, combining metal nanoparticles with immunizing and other chemicals, and combining the SERS technology with related techniques. As SERS technology continues to develop and improve, it is expected to become an even more widely used and effective tool for detecting residues of LMP in meat.

show abstract

“…A number of methods have been developed to determine β-agonists, mainly including instrumental and immunological analysis . Instrument methods such as liquid chromatography tandem mass spectrometry (LC–MS/MS), high-performance liquid chromatography (HPLC), and gas chromatography–mass spectrometry (GC–MS) have the merits of high specificity and sensitivity. Yet, they require costly facility and practised operators, limiting the application in field rapid screening .…”

Section: Introductionmentioning

confidence: 99%

Ultrasensitive Magnetic Assisted Lateral Flow Immunoassay Based on Chiral Monoclonal Antibody against R-(−)-Salbutamol of Broad-Specificity for 38 β-Agonists Detection in Swine Urine and Pork

Liang

Liu

Xie³

et al. 2022

J. Agric. Food Chem.

View full text Add to dashboard Cite

Screening for ″zero tolerance″ β-agonists requires broad-specificity and sensitivity methods. Herein, R-(−)-salbutamol (SAL) is chirally separated and designed as a hapten, and a monoclonal antibody (mAb) was first prepared with an IC50 of 0.27 ng/mL, which can recognize 38 β-agonists simultaneously. The broad-specificity of chiral mAb was explored by molecular simulation technology. Magnetic nanoparticles (MNPs) were then synthesized and applied as a signal tracer to develop a lateral flow immunoassay (LFIA). The limits of detection of MNPs-LFIA for SAL in swine urine and pork were 0.05 and 0.09 μg/kg, which was (2–125)-fold lower than that of the reported LFIAs. The recoveries were between 95.8 and 116.7%, with the coefficient of variation from 2.7 to 15.4%. Parallel analysis of 44 samples by commercial ELISA kits confirmed the reliability. Therefore, our work not only provides a broad-specificity and ultrasensitive method for β-agonists but also suggests that chirality is the new general theory that guided the rational hapten design.

show abstract

Preparation of a teicoplanin-bonded chiral stationary phase for simultaneous determination of clenbuterol and salbutamol enantiomers in meat by LC-MS/MS

Cited by 12 publications

References 36 publications

Recent progress in the development of chiral stationary phases for high‐performance liquid chromatography

Recent progress in the development of chiral stationary phases for high‐performance liquid chromatography

Advance in Detection Technique of Lean Meat Powder Residues in Meat Using SERS: A Review

Ultrasensitive Magnetic Assisted Lateral Flow Immunoassay Based on Chiral Monoclonal Antibody against R-(−)-Salbutamol of Broad-Specificity for 38 β-Agonists Detection in Swine Urine and Pork

Contact Info

Product

Resources

About