Preparation of a 3D printable high-performance GelMA hydrogel loading with magnetic cobalt ferrite nanoparticles

Shi, Yiwan; Wang, Zhaozhen; Zhou, Xinting; Lin, Chengxiong; Chen, Chao; Gao, Beibei; Xu, Weikang; Zheng, Xiaofei; Wu, Tingting; Wang, Huajun

doi:10.3389/fbioe.2023.1132192

Cited by 5 publications

(1 citation statement)

References 70 publications

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“…In addition, MeCFO at a concentration of 50 µg ml −1 revealed both decreased activity of cells in osteosarcoma cells and fostered osteogenic differentiation of mBMSCs. The outcomes suggested that the developed hydrogel could serve as a favorable therapeutic approach for the treatment of osteosarcoma and bone reconstruction after resection [202].…”

Section: D Printing/bioprinting In Tissue Engineeringmentioning

confidence: 99%

Unveiling the versatility of gelatin methacryloyl hydrogels: a comprehensive journey into biomedical applications

Pramanik,

Alhomrani,

Alamri

et al. 2024

Biomed. Mater.

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Gelatin methacryloyl (GelMA) hydrogels have gained significant recognition as versatile biomaterials in the biomedical domain. GelMA hydrogels emulate vital characteristics of the innate extracellular matrix (ECM) by integrating cell-adhering and matrix metalloproteinase-responsive peptide motifs. These features enable cellular proliferation and spreading within GelMA-based hydrogel scaffolds. Moreover, GelMA displays flexibility in processing, as it experiences crosslinking when exposed to light irradiation, supporting the development of hydrogels with adjustable mechanical characteristics. The drug delivery landscape has been reshaped by GelMA hydrogels, offering a favorable platform for the controlled and sustained release of therapeutic actives. The tunable physicochemical characteristics of GelMA enable precise modulation of the kinetics of drug release, ensuring optimal therapeutic effectiveness. In tissue engineering, GelMA hydrogels perform an essential role in the design of the scaffold, providing a biomimetic environment conducive to cell adhesion, proliferation, and differentiation. Incorporating GelMA in three-dimensional printing further improves its applicability in drug delivery and developing complicated tissue constructs with spatial precision. Wound healing applications showcase GelMA hydrogels as bioactive dressings, fostering a conducive microenvironment for tissue regeneration. The inherent biocompatibility and tunable mechanical characteristics of GelMA provide its efficiency in the closure of wounds and tissue repair.GelMA hydrogels stand at the forefront of biomedical innovation, offering a versatile platform for addressing diverse challenges in drug delivery, tissue engineering, and wound healing. This review provides a comprehensive overview, fostering an in-depth understanding of GelMA hydrogel’s potential impact on progressing biomedical sciences.

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Section: D Printing/bioprinting In Tissue Engineeringmentioning

confidence: 99%

Unveiling the versatility of gelatin methacryloyl hydrogels: a comprehensive journey into biomedical applications

Pramanik,

Alhomrani,

Alamri

et al. 2024

Biomed. Mater.

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The effect of adding cobalt ferrite (CoFe3O4) nanoparticles as fillers on rheological and structural behaviour of gum ghatti-cl-poly(NIPAm) hydrogels

Dave,

Macwan,

Kamaliya

2024

Mech Time-Depend Mater

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Mg alloys with antitumor and anticorrosion properties for orthopedic oncology: A review from mechanisms to application strategies

Lin,

Wei,

Yang

2024

APL Bioengineering

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As a primary malignant bone cancer, osteosarcoma (OS) poses a great threat to human health and is still a huge challenge for clinicians. At present, surgical resection is the main treatment strategy for OS. However, surgical intervention will result in a large bone defect, and some tumor cells remaining around the excised bone tissue often lead to the recurrence and metastasis of OS. Biomedical Mg-based materials have been widely employed as orthopedic implants in bone defect reconstruction, and, especially, they can eradicate the residual OS cells due to the antitumor activities of their degradation products. Nevertheless, the fast corrosion rate of Mg alloys has greatly limited their application scope in the biomedical field, and the improvement of the corrosion resistance will impair the antitumor effects, which mainly arise from their rapid corrosion. Hence, it is vital to balance the corrosion resistance and the antitumor activities of Mg alloys. The presented review systematically discussed the potential antitumor mechanisms of three corrosion products of Mg alloys. Moreover, several strategies to simultaneously enhance the anticorrosion properties and antitumor effects of Mg alloys were also proposed.

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Preparation of a 3D printable high-performance GelMA hydrogel loading with magnetic cobalt ferrite nanoparticles

Cited by 5 publications

References 70 publications

Unveiling the versatility of gelatin methacryloyl hydrogels: a comprehensive journey into biomedical applications

Unveiling the versatility of gelatin methacryloyl hydrogels: a comprehensive journey into biomedical applications

The effect of adding cobalt ferrite (CoFe3O4) nanoparticles as fillers on rheological and structural behaviour of gum ghatti-cl-poly(NIPAm) hydrogels

Mg alloys with antitumor and anticorrosion properties for orthopedic oncology: A review from mechanisms to application strategies

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