Preparation, characterization and in vitro biological response of simultaneous co-substitution of Zr+4/Sr+2 58S bioactive glass powder

Moghanian, Amirhossein; Zohourfazeli, Mohammadamin; Tajer, Mahzad Haji Mahdi; Miri, Zahra; Hosseini, SeyedMohammad; Rashvand, Ali

doi:10.1016/j.ceramint.2020.11.139

Cited by 26 publications

(1 citation statement)

References 52 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In other words, the biomaterial is not the only kind of material that does not have any toxicity and harmful effects on the human body but also can form hydroxyapatite (HA) that is important. When bioactive material is soaked in biological fluids such as simulated body fluid (SBF), the HA layer can be formed on their surfaces 6–8 . According to its biological passivity, it can be used inside the human body 9 .…”

Section: Introductionmentioning

confidence: 99%

Characterization, in vitro bioactivity and biological studies of sol‐gel‐derived TiO₂ substituted 58S bioactive glass

Moghanian

Nasiripour

Koohfar

et al. 2021

Int J Applied Ceramic Tech

Self Cite

View full text Add to dashboard Cite

Bioactive glasses (BGs) have been used for bone formation and bone repair processes in recent years. This study investigated the titanium substitution effect on 58S BGs (Ti‐BGs) 60SiO2‐(36 − X)CaO‐4P2O5‐XTiO2 (X = 0, 3, and 5 mol.%) prepared by the sol‐gel technique, and the main goal was to find the optimum amount of titanium in Ti‐BGs. Synthesized BGs, which were investigated after immersion in simulated body fluid (SBF), were tested by X‐ray diffraction (XRD) analysis, Fourier transform infrared spectroscopy (FTIR), and scanning electron microscopy. Moreover alkaline phosphate (ALP) activity, 3‐(4,5dimethylthiazol‐2‐yl)‐2,5‐diphenyltetrazolium bromide (MTT) assay, and antibacterial studies were employed to investigate the biological properties of Ti‐BGs. According to the FTIR and XRD test results, hydroxyapatite (HA) formation on Ti‐BGs surfaces was confirmed. Meanwhile, the presence of 5 mol.% compared to 3 mol.% increased the HA grain distribution and their size on the Ti‐BGs surface. Additionally, MTT and ALP results confirmed that the optimal amount of titanium substitution in BG was 5 mol.%. Since 5 mol.% Ti incorporated BG (BG‐5) had the highest biocompatibility level, antibacterial properties, maximum cell proliferation, and ALP activity among the synthesized Ti‐BGs, it is presented as the best candidate for further in vivo investigations.

show abstract

Section: Introductionmentioning

confidence: 99%

Characterization, in vitro bioactivity and biological studies of sol‐gel‐derived TiO₂ substituted 58S bioactive glass

Moghanian

Nasiripour

Koohfar

et al. 2021

Int J Applied Ceramic Tech

Self Cite

View full text Add to dashboard Cite

show abstract

Exploring the advancements in surface-modified bioactive glass: enhancing antibacterial activity, promoting angiogenesis, and modulating bioactivity

Taye,

Ningsih,

Shih

2024

J Nanopart Res

View full text Add to dashboard Cite

Nonlinear Viscoelastic Modeling of Synthesized Silicate-Based Bioactive Glass/Polysulfone Composite: Theory and Medical Applications

Moghanian

Pazhouheshgar

Ghorbanoghli

2021

Silicon

View full text Add to dashboard Cite

Preparation, characterization and in vitro biological response of simultaneous co-substitution of Zr+4/Sr+2 58S bioactive glass powder

Cited by 26 publications

References 52 publications

Characterization, in vitro bioactivity and biological studies of sol‐gel‐derived TiO₂ substituted 58S bioactive glass

Characterization, in vitro bioactivity and biological studies of sol‐gel‐derived TiO₂ substituted 58S bioactive glass

Exploring the advancements in surface-modified bioactive glass: enhancing antibacterial activity, promoting angiogenesis, and modulating bioactivity

Nonlinear Viscoelastic Modeling of Synthesized Silicate-Based Bioactive Glass/Polysulfone Composite: Theory and Medical Applications

Contact Info

Product

Resources

About

Preparation, characterization and in vitro biological response of simultaneous co-substitution of Zr+4/Sr+2 58S bioactive glass powder

Cited by 26 publications

References 52 publications

Characterization, in vitro bioactivity and biological studies of sol‐gel‐derived TiO2 substituted 58S bioactive glass

Characterization, in vitro bioactivity and biological studies of sol‐gel‐derived TiO2 substituted 58S bioactive glass

Exploring the advancements in surface-modified bioactive glass: enhancing antibacterial activity, promoting angiogenesis, and modulating bioactivity

Nonlinear Viscoelastic Modeling of Synthesized Silicate-Based Bioactive Glass/Polysulfone Composite: Theory and Medical Applications

Contact Info

Product

Resources

About

Characterization, in vitro bioactivity and biological studies of sol‐gel‐derived TiO₂ substituted 58S bioactive glass

Characterization, in vitro bioactivity and biological studies of sol‐gel‐derived TiO₂ substituted 58S bioactive glass