Preparation, Characterization and Biological Studies of Adducts of Bis(O-isopropyldithiocarbonato)oxovanadium(IV) with Nitrogen Donor Ligands

Abstract

A series of adducts of bis(O-isopropyldithiocarbonato)oxovanadium(IV) with substituted pyridines have been synthesized by treating bis(O-isopropyldithiocarbonato)oxovanadium(IV) with substituted pyridines in acetone in equimolar ratios. Analytical results show that the adducts have 1:1 stoichiometry with general formula VO(O-isopropyldithiocarbonato)2L where L = 2 and 3-bromopyridine; 4-acetylpyridine; 3-hydroxypyridine; 2-methoxypyridine; 2-amino-3-methylpyridine; 2-amino-4-methylpyridine; 2-amino-6-methylpyridine). The addition complexes have been characterized by elemental analysis, conductivity measurements, magnetic susceptibility measurements, infrared and electronic spectral studies. These studies suggest a distorted octahedral structure and paramagnetic nature of the adducts. Antifungal activity of some adducts have been carried out against the fungal strain Sclerotium rolfsii.