Preparation, characterization and biological activity of phosphorylated surface deacetylated chitin nanofibers

Yu, Sophia; Duan, Mengxia; Zeng, Ronghuai; Chen, Fujie; Zhong, Weiquan; Sun, Jishuai; Xu, Jingting; Li, Danjie; Yan, Zheng; Liu, Xiaoyan; Pang, Jie; Wu, Chunhua

doi:10.1016/j.ijbiomac.2023.123492

Cited by 7 publications

(3 citation statements)

References 40 publications

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“…[9,29,28] The absorbance near 1430 cm À 1 was related to CÀ H variable angle vibration. [30] Compared with ASP, the strong absorption of ASPPs near 1270 cm À 1 was caused by the introduction of P=O in the sugar ring, and the absorption near 980 cm À 1 was attributed to the PÀ O-C stretching vibration, indicating that the phosphorylation modification of ASP was successful . [31] Triple helix structure analysis Compared with the Congo red, the λ max of the formed complex will be red-shifted.…”

Section: Uv-vis Spectroscopymentioning

confidence: 99%

Phosphorylation Modification, Structural Characterization, Antioxidant and DNA Protection Capacities of Polysaccharides from Asarum Sieboldii Miq

Yang,

Wang,

Zhang

et al. 2024

Chemistry & Biodiversity

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Polysaccharide from Asarum sieboldii Miq (ASP) was extracted and five phosphorylation polysaccharides with different degree of substitution were obtained, namely ASPP1, ASPP2, ASPP3, ASPP4, and ASPP5 (ASPPs). The physical and chemical structure and biological activities were studied. The results suggested that the carbohydrate and protein content were reduced while uronic acid was increased after phosphorylation modification. The molecular weight of ASPPs was significantly lower than that of ASP. ASPPs were acidic heteropolysaccharides mainly composed of galacturonic acid, galactose, glucose, fructose, and arabinose. The UV‐vis spectrum indicated that the polysaccharides did not contain nucleic acid or protein after modification. The Fourier transform infrared spectrum demonstrated that ASPPs contained characteristic absorption peaks of P=O and P‐O‐C near 1270 and 980 cm‐1. ASPPs presented a triple helix conformation, but it was not presented in ASP. The scanning electron microscopy analysis showed that the surface topography and particle structure of ASP were different after modification. Compared with ASP, ASPPs enhanced the activity to scavenge DPPH and ABTS free radicals and possessed more protective ability to DNA oxidation caused by OH·, GS·, and AAPH free radicals. These results suggest that chemical modification is beneficial for the exploitation and utilization of natural polysaccharides.

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Section: Uv-vis Spectroscopymentioning

confidence: 99%

Phosphorylation Modification, Structural Characterization, Antioxidant and DNA Protection Capacities of Polysaccharides from Asarum Sieboldii Miq

Yang,

Wang,

Zhang

et al. 2024

Chemistry & Biodiversity

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“…2.6 Characterization of nanocomposite lms 2.6.1 Fourier transform infrared (FT-IR) spectroscopy. The chemical structure of the nanocomposite lms was analyzed by using a FT-IR spectrometer (Thermo Nicolette 6700, Thermo Nicolet, USA) with reference and slight modication to Yu et al 19 The samples were mixed with KBr powder in the ratio of 1 : 100 and pressed into thin sheets, then scanned in the wave number range of 4000-400 cm −1 and the spectra were recorded.…”

Section: Rheological Properties Of Composite Solutionsmentioning

confidence: 99%

Effects of oregano essential oil Pickering emulsion and ZnO nanoparticles on the properties and antibacterial activity of konjac glucomannan/carboxymethyl chitosan nanocomposite films

Pan,

Zhong,

et al. 2024

RSC Adv.

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“…It is worth noting that natural polysaccharides exhibit significant biological activities. [103] However, the phosphorylation modification of polysaccharides may increase their biological activities to a certain extent. Therefore, we still need to develop more polysaccharides modification methods to provide an important material basis for the development of new drugs in the future.…”

Section: Other Activitiesmentioning

confidence: 99%

Modification, Structure Identification, and Biological Activities of Phosphorylated Polysaccharides: A Review

Gao,

Liu,

Dai

et al. 2024

Starch Stärke

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Polysaccharides are a kind of biological macromolecule, which widely exists in plants, fungi, animals, microorganisms, and other organisms. Polysaccharides exhibit various biological activities such as immunological regulation, antioxidation, antitumor, antiinflammatory, regulating intestinal flora, and protecting liver. These biological activities depend on their structure and physicochemical properties including monosaccharide composition, molecular weight (Mw), spatial configuration, etc. However, biological activities of polysaccharides are hardly comparable to synthetic drugs due to their inherent physicochemical properties. Therefore, structural modification of polysaccharides is an effective way to enhance their biological activities and promote the presentation of bioactivity. At present, phosphorylation modification is a common chemical modification method, which can effectively improve the biological activities of polysaccharides. However, there are limited reports on the synthesis, structure identification, and biological activities of phosphorylated polysaccharides. In view of this, the synthesis methods, structure identification methods, and biological activities of phosphorylated polysaccharides are reviewed in this paper. The findings can provide useful guidance for the research, production, and application of phosphorylated polysaccharides in functional foods and therapeutic agents.

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Preparation, characterization and biological activity of phosphorylated surface deacetylated chitin nanofibers

Cited by 7 publications

References 40 publications

Phosphorylation Modification, Structural Characterization, Antioxidant and DNA Protection Capacities of Polysaccharides from Asarum Sieboldii Miq

Phosphorylation Modification, Structural Characterization, Antioxidant and DNA Protection Capacities of Polysaccharides from Asarum Sieboldii Miq

Effects of oregano essential oil Pickering emulsion and ZnO nanoparticles on the properties and antibacterial activity of konjac glucomannan/carboxymethyl chitosan nanocomposite films

Modification, Structure Identification, and Biological Activities of Phosphorylated Polysaccharides: A Review

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