Preparation, Characterization, and Antioxidant Properties of Self-Assembled Nanomicelles of Curcumin-Loaded Amphiphilic Modified Chitosan
Qizhou Chen,
Yuwei Jiang,
Linlan Yuan
et al.
Abstract:Curcumin (Cur) is a phytochemical with various beneficial properties, including antioxidant, anti-inflammatory, and anticancer activities. However, its hydrophobicity, poor bioavailability, and stability limit its application in many biological approaches. In this study, a novel amphiphilic chitosan wall material was synthesized. The process was carried out via grafting chitosan with succinic anhydride (SA) as a hydrophilic group and deoxycholic acid (DA) as a hydrophobic group; 1H-NMR, FTIR, and XRD were empl… Show more
This work used three types of molecules to construct targeted nanoparticles that can enhance the anti-tumor effect of Cur through active and passive targeting used three moleculars to construct targeted nano.
This work used three types of molecules to construct targeted nanoparticles that can enhance the anti-tumor effect of Cur through active and passive targeting used three moleculars to construct targeted nano.
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