Preparation and properties of porous particles from trimethylolpropane trimethacrylate

Abstract

Spherical macroporous particles, intended for use as carrier particles in various types of column operations, were prepared by suspension and microsuspension polymerization of trimethylolpropane trimethacrylate (TRIM), in the presence of various amounts of porogenic agents (toluene or mixtures of toluene and isooctane). The texture and properties of the particles varied markedly with the amount and * Systematic UIPAC name: 2,2-bis(methacryloyloxymethyl)butyl methacrylate. 0 1991 Hiithig & Wepf Verlag, Base1 CCC 0003-3146/91/$04.00 113 P. Reinholdsson, T. Hargitai, R. Isaksson, B. Tornell Isooktan) hergestellt. Textur und Eigenschaften der Partikel variierten deutlich mit dem Anteil und der Zusammensetzung des porogenen Reagens und wurden zusatzlich durch die Wahl des Suspensionstabilisators beeinflufit. Die makroporosen Partikel wiesen ein Gesamtporenvolumen von 0,4 bis 3,6 cm3/g und eine spezifische Oberflache von 7 bis >450 m2/g auf. Alle Partikel enthielten Makroporen und, aufier den Teilchen mit sehr niedriger spezifischer Oberflache, einen gewissen Anteil an Mikroporen (Durchmesser < 60 A). Durch Erniedrigung der Monomerkonzentration und Erhdhung des Isooktan-Gehaltes im porogenen Reagens auf 50 Gew.-To konnte das Auftreten von Mikroporen vollstandig unterdriickt werden. Das Erhohen des Isooktan-Gehaltes fiihrte zu einem vergrofierten Gesamtporenvolumen und zu einem verringerten Quellvermogen der Polymermatrix in Toluol. Der Einflufi einer Hitzebehandlung bei 130 "C und eines Aufpfropfens von Polymethylmethacrylat auf die Partikeleigenschaften wurde ebenfalls untersucht. Die Menge an nicht umgesetzten Doppelbindungen in den Partikeln konnte durch Variation der Polymerisationstemperatur verandert werden. Das Vorhandensein leicht zuglnglicher Doppelbindungen ist wichtig, da sie zur Funktionalisierung der festen makroporosen Partikel verwendet werden konnen.

Preparation and characterization of grafted imprinted monolith for capillary electrochromatography

“…In this work, TRIM monolith is chosen as core monolith since poly‐TRIM indicated pendant double bonds , by which graft polymerization can occur. To obtain a core monolith with good permeability, scouting experiments about polymerization parameters were performed, including the content of TRIM, the composition of the porogen, the amount of AIBN, reaction time, and reaction temperature (data not shown).…”

Synthesis of core‐shell structured carboxylated microparticles with a straightforward procedure and their evaluation as a polymer support

“…Although the preparation of polyTRIM particles by a suspension technique avoids some of the disadvantages of the bulk polymerization, it leads to a large size distribution of the particles and their characteristics and purity depending on the stabilizer used. 18 As a consequence, we have chosen the precipitation polymerization as a technique for the preparation of the polyTRIM grafting support, a less laborious, cheaper, and cleaner preparative alternative than suspension and bulk polymerization. Particle size, porosity, amount, and availability of double bonds are some of the most important characteristics of polyTRIM particles.…”

“…[14][15][16] The concentration of unpolymerized methacrylate residues can be controlled by selecting appropriate polymerization parameters. 14,17,18 The high stability of the poly-TRIM matrix and its relatively low tendency to swell in different solvents prevent copolymerization within the solid particle. The high reactivity of the methacrylic groups guarantees the achievement of the required degree of functionalization.…”

The release of ibuprofen sodium salt from permanently porous poly(hydroxyethyl methacrylate-co-trimethylolpropane trimethacrylate) resins

“…The fairly hydrophobic character of the polymer results in its relatively low tendency to swell in different solvents, especially of hydrophilic character, and as a consequence, it is only slightly sensitive to the surrounding solvent [2,14e17]. The presence of unpolymerized methacrylate groups makes it possible to easily obtain the desirable physical and chemical properties of original poly(TRIM) polymer by grafting them with different functional monomers [4,18,19]. Simultaneously, by using TRIM as a multifunctional crosslinking agent and employing the suspension polymerization a wide range of copolymers of desired chemical character were fabricated and intensively investigated [3,20e22].…”