Preparation and properties of porous Ti–10Mo alloy by selective laser sintering

Xie, Fangxia; He, Xiaocong; Lu, Xin; Cao, Shunli; Qu, Xuanhui

doi:10.1016/j.msec.2012.11.037

Cited by 32 publications

(19 citation statements)

References 27 publications

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“…1c). This is a standard technique for 3D printing of metals (63)(64)(65)(66)(67)(68)(69). The powders or starting materials that could be used include; polyamides, polystyrenes or polycarbonates (70).…”

Section: Selective Laser Sintering (Sls) 3d Printingmentioning

confidence: 99%

Emergence of 3D Printed Dosage Forms: Opportunities and Challenges

et al. 2016

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The recent introduction of the first FDA approved 3D-printed drug has fuelled interest in 3D printing technology, which is set to revolutionize healthcare. Since its initial use, this rapid prototyping (RP) technology has evolved to such as extent that it is currently being used in a wide range of applications including in tissue engineering, dentistry, construction, automotive and aerospace. However, in the pharmaceutical industry this technology is still in its infancy and its potential yet to be fully explored. This paper presents various 3D printing technologies such as stereolithographic, powder based, selective laser sintering, fused deposition modelling and semi-solid extrusion 3D printing. It also provides a comprehensive review of previous attempts at using 3D printing technologies on the manufacturing dosage forms with a particular focus on oral tablets. Their advantages particularly with adaptability in the pharmaceutical field have been highlighted, including design flexibility and control and manufacture which enables the preparation of dosage forms with complex designs and geometries, multiple actives and tailored release profiles. An insight into the technical challenges facing the different 3D printing technologies such as the formulation and processing parameters is provided. Light is also shed on the different regulatory challenges that need to be overcome for 3D printing to fulfil its real potential in the pharmaceutical industry.

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Section: Selective Laser Sintering (Sls) 3d Printingmentioning

confidence: 99%

Emergence of 3D Printed Dosage Forms: Opportunities and Challenges

et al. 2016

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“…As an additive and rapid prototyping manufacturing technology, selective laser sintering (SLS) involves the use of a laser to sinter the powders, focusing the laser automatically at points in space defined by a three-dimensional model, binding the material together to create a solid structure in a layer-by-layer manner [24,25].…”

Section: Selective Laser Sinteringmentioning

confidence: 99%

“…The porous structure of Ti-10Mo alloys prepared by SLS is characterized by irregular shaped pores and uniform pore distribution. A pore size of 120 to 130 lm of porous Ti-10Mo alloy with porosity of 61 to 63 % is favorable to bone tissue ingrowth [24,25].…”

Section: Selective Laser Sinteringmentioning

confidence: 99%

“…The latter is relevant to biochemical compatibility. The Young's moduli of the aforementioned metals ranging from 120 to 232 GPa are substantially larger than those of cancellous (1 -2 GPa) and cortical (20)(21)(22)(23)(24)(25)(26)(27) bones [5]. Therefore, stress shielding, a critical issue in hard tissue replacement, which originates from the mismatch of Young's modulus, may cause osteoporosis of the surrounding bone tissue.…”

Section: Introductionmentioning

confidence: 99%

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Current developments of biomedical porous Ti–Mo alloys

Wang

2017

International Journal of Materials Research

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Current developments of biomedical porous Ti-Mo alloysAs a biomedical hard tissue implant candidate, porous Ti-Mo alloy has received considerable attention because of its special porous structure, appropriate Young's modulus and compressive strength as well as good corrosion resistance. As a bioactive coating, hydroxyapatite is commonly used to cover the surface of bioinert metallic prostheses due to its excellent biocompatibility, bone-like structure and composition. This article reviews the current developments and the relationships between the fabrication methods, porous structure, mechanical properties, bioactive surface modification and corrosion behavior of porous Ti-Mo alloy used for hard tissue implant application. Furthermore, the future research directions are discussed to optimize the porous structure and improve the properties of porous Ti-Mo alloys.

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“…Recently, there are some reports about the porous TiMo alloys prepared by different methods, such as vacuum sintering [9,10], gelcasting [23], selective laser sintering [24,25] and atmosphere protection conventional sintering [21,26]. Microwave sintering is a new powder metallurgy sintering method to prepare the porous metallic materials, such as porous NiTi alloys [27,28], porous Ti6Al4V/ TiC/HA composites [29] and porous Ti/CaP composites [30].…”

Section: Introductionmentioning

confidence: 99%

Preparation and bioactive surface modification of the microwave sintered porous Ti-15Mo alloys for biomedical application

Zhang

Bao

et al. 2017

Sci. China Mater.

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Biomedical porous Ti-15Mo alloys were prepared by microwave sintering using ammonium hydrogen carbonate (NH 4 HCO 3 ) as the space holder agent to adjust the porosity and mechanical properties. The porous Ti-15Mo alloys are dominated by β-Ti phase with a little α-Ti phase, and the proportion of α and β phase has no significant difference as the NH 4 HCO 3 content increases. The porosities and the average pore sizes of the porous Ti-15Mo alloys increase with increase of the contents of NH 4 HCO 3 , while all of the compressive strength, elastic modulus and bending strength decrease. However, the compressive strength, bending strength and the elastic modulus are higher or close to those of natural bone. The surface of the porous Ti-15Mo alloy was further modified by hydrothermal treatment, after which Na 2 Ti 6 O 13 layers with needle and flake-like clusters were formed on the outer and inner surface of the porous Ti-15Mo alloy. The hydrothermally treated porous Ti-15Mo alloy is completely covered by the Ca-deficient apatite layers after immersed in SBF solution for 14 d, indicating that it possesses high apatiteforming ability and bioactivity. These results demonstrate that the hydrothermally treated microwave sintered porous Ti15Mo alloys could be a promising candidate as the bone implant.

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Preparation and properties of porous Ti–10Mo alloy by selective laser sintering

Cited by 32 publications

References 27 publications

Emergence of 3D Printed Dosage Forms: Opportunities and Challenges

Emergence of 3D Printed Dosage Forms: Opportunities and Challenges

Current developments of biomedical porous Ti–Mo alloys

Preparation and bioactive surface modification of the microwave sintered porous Ti-15Mo alloys for biomedical application

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