Preparation and Performance Evaluation of Antibacterial Melt-Spun Polyurethane Fiber Loaded with Berberine Hydrochloride

Abstract

(1) Background: Bacterial infections have long threatened global public safety; hence, it is significant to continuously develop antibacterial fibers that are closely related to people’s daily lives. Berberine hydrochloride is a natural antibacterial agent that has application prospects in the preparation of antibacterial fibers. (2) Methods: This study firstly verified the antibacterial properties of berberine hydrochloride and its possible antibacterial mechanism. Thereafter, berberine hydrochloride was introduced into the self-made melt-spun polyurethane fiber through optimized coating technology. The performance of coating modified polyurethane fiber has been systematically evaluated, including its antibacterial properties, mechanical properties, and surface wettability. (3) Results: Results show that the antibacterial polyurethane fiber with desirable comprehensive properties is expected to be used in the biomedical fields. (4) Conclusions: The research also provides a reference for the development and application of other natural antibacterial ingredients in fiber fields.

Environmentally Friendly and Broad–Spectrum Antibacterial Poly(hexamethylene guanidine)–Modified Polypropylene and Its Antifouling Application

“…Organic small–molecule antimicrobials come from a wide variety of sources and are efficient and convenient to use. However, adding organic small–molecule antimicrobials into the matrix as antibacterial agents causes problems such as poor heat resistance, easy decomposition, and easy precipitation [ 27 , 28 , 29 ]. Most of the antibacterial agents mentioned above are added to the matrix by physical blending.…”

Antibacterial and mildew‐proof aramid fiber III: The chlorination mechanism through experimental and computational investigation

“…The agar plate method was used to evaluate the antibacterial properties against S. aureus and E. coli under optimal culture conditions and temperature 22,23 . Two pieces of 10 mg F‐2 fiber were placed in two centrifuge tubes, and 1 mL of bacterial suspension for S. aureus or E. coli (with a concentration of 1 × 10 4 CFU/mL) was added to each tube.…”

“…The agar plate method was used to evaluate the antibacterial properties against S. aureus and E. coli under optimal culture conditions and temperature. 22,23 Two pieces of 10 mg F-2 fiber were placed in two centrifuge tubes, and 1 mL of bacterial suspension for S. aureus or E. coli (with a concentration of 1 Â 10 4 CFU/mL) was added to each tube. The tubes were incubated at 37 C with shaking at 200 r/min for 1 h. After the incubation, 100 μL of bacterial suspension was withdraw from each tube and uniformly spread on nutrient agar (NA) solid medium.…”

High-Performance, Degradable, Self-Healing Bio-Based Nanocomposite Coatings with Antibacterial and Antioxidant Properties

“…By contrast, although natural antimicrobials had poor heat resistance and short antimicrobial duration, they were highly valued by researchers for their safety, non-toxicity, cost-effectiveness, and antioxidant properties. Zhao et al [ 10 ] introduced berberine hydrochloride with broad-spectrum antibacterial activity into polyurethane fiber and found that the composite polyurethane fiber can inhibit the activity of respiratory chain hydrogenase in Escherichia coli ( E. coli ) and Staphylococcus aureus ( S. aureus ), thus inhibiting the growth of bacteria. At the same time, it can also destroy the bacterial cell wall and cell membrane, resulting in the leakage of intracellular macromolecules.…”