Preparation and optimization of chitosan/polyethylene oxide nanofiber diameter using artificial neural networks

Design and manufacture of neural tissue engineering scaffolds using hyaluronic acid and polycaprolactone nanofibers with controlled porosity

“…During the electrospinning process, strong electrostatic field is applied to the polymer solution. When the electrical field overcomes the surface tension of solution, the solution is thrown with intensity to the rotating collector [12][13][14].This method is a powerful technique for producing fibers with controlled diameter and morphology [15]. Morphology of fibers is one of important parameters to control the properties of electrospun scaffolds in tissue engineering [16,17].…”

Biocompatibility and nanostructured materials: applications in nanomedicine

“…Their use in diverse areas has been vastly explored in recent years, offering great advantages over conventional materials. In particular, the engineered nanomaterials have been widely investigated for the biomedical applications, including development of new diagnostic tools such as nanobiosensors and precise imaging modalities, novel therapeutics based on targeted drug delivery systems, and scaffolds for tissue engineering (Chang 2014, Karimi et al 2015, Ketabchi et al 2016, Naghibzadeh and Adabi 2014. Due to the increasing usage of nanomaterials in various fields of science and technology, the concerns have been emerged about their safety, biocompatibility, and toxicity.…”

“…Several nanostructured materials have been explored for the biomedical applications. The most commonly studied materials are based on carbon, silica, and metals in different shapes (i.e., spheres, tubes, and rods) (Adabi et al 2011, Ketabchi et al 2016, Shakoori et al 2015, Tavakol et al 2014. The toxicity and biocompatibility of these materials depends on several factors such as the size, surface area, functional groups, concentration, and dosage (Foldvari and Bagonluri 2008).…”

Pain management using nanotechnology approaches

“…Nanomaterials design have been broadly inspect for biomedical applications, including advancement of new demonstrative instruments, for example, novel therapeutics for targeted drug delivery, nanobiosensors and technique modalities and platforms for tissue regeneration [2][3][4]. Biocompatibility, have been taken into account to avoid their toxicity on entering into the blood stream.…”