1957
DOI: 10.3181/00379727-96-23551
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Preparation and Inactivation of Purified Poliovirus: Comparison of Vaccines Derived from Mahoney and Parker Poliovirus

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1958
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Cited by 14 publications
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“…The results reported here confirm observations made by others ( 7 , 15,16) that formalin treated poliovirus can be used as antigen in C F tests. However, the titer of the antigen is low, and it is therefore necessary to use the C F serum titer in order to express the relative potency of various formalin treated polio antigens.…”
Section: Discussionsupporting
confidence: 92%
“…The results reported here confirm observations made by others ( 7 , 15,16) that formalin treated poliovirus can be used as antigen in C F tests. However, the titer of the antigen is low, and it is therefore necessary to use the C F serum titer in order to express the relative potency of various formalin treated polio antigens.…”
Section: Discussionsupporting
confidence: 92%
“…In contrast to departure from first-order kinetics of inactivation with purified material in the present work and that of Lycke (1958a), first-order kinetics were observed by Charney et al (1957). The reason for the discrepancy is not apparent, but it may lie in differences of techniques employed in inactivation or assay.…”
Section: Discussioncontrasting
confidence: 92%