Preparation and Chromatographic Application of β-Cyclodextrin Molecularly Imprinted Microspheres for Paeoniflorin

Macromol. Rapid Commun.

et al. 2021

Molecular imprinting polymers (MIPs), generally considered as artificial mimics that are comparable to natural receptor, are polymers with tailor‐made specific recognition sites complementary to the template molecules in shape and size. As a class of supramolecular compounds, cyclodextrins (CDs) are flourishing in the field of molecular imprinting with their unique structural properties. This review presents recent advances in application of MIPs based on CDs during the past five years. The discussion is grouped according to the different role of CDs in MIPs, that is, functional monomer, carrier modifier, etc. Main focus is the application of CD‐based MIP on sample preparation, detection, and sensing. Additionally, drug delivery with CD‐based MIP is also briefly discussed. Finally, challenges and future prospects of application of CDs in MIP are elaborated.

Section: Other Molecularly Imprinted Polymers Based On Cyclodextrinmentioning

confidence: 99%

Recent Advances of Molecularly Imprinted Polymers Based on Cyclodextrin

Zhao

Wang

Macromol. Rapid Commun.

et al. 2021

“…In the field of molecular imprinting, for the quantitative analysis of the combination of the template and the adsorbent, the Scatchard model is used [7]:trueQeCe=(Qmax−Qe)KD where K D is the dissociation constant; Q max is the maximum adsorption capacity of Re; and C e is the equilibrium concentration of Re.…”

Section: Methodsmentioning

confidence: 99%

“…Third, the binding sites, which are complementary to the template molecules in terms of size, structure, and site of the functional groups, are formed after the removal of the template by chemical reaction or extraction [ 5 ]. Therefore, the MIPs obtained have the characteristics of selectivity and recognition of the desired target [ 6 , 7 , 8 ]. Compared with some natural biomolecular recognition systems, such as antibody and antigen, receptor and ligand or enzyme and substrate, the MIPs have some significant advantages including high resistance to temperature, pressure, acid, alkali, metal ion, and organic solvents.…”

Section: Introductionmentioning

confidence: 99%

Mechanism Analysis of Selective Adsorption and Specific Recognition by Molecularly Imprinted Polymers of Ginsenoside Re

Cong

et al. 2018

Polymers

Self Cite

In this article, the molecularly imprinted polymers (MIPs) of ginsenoside Re (Re) were synthesized by suspension polymerization with Re as the template molecule, methacrylic acid (MAA) as the functional monomers, and ethyl glycol dimethacrylate (EGDMA) as the crosslinker. The MIPs were characterized by Fourier transform infrared spectroscopy (FTIR), Field emission scanning electron microscopy (FESEM), and surface porosity detector, and the selective adsorption and specific recognition of MIPs were analyzed using the theory of kinetics and thermodynamics. The experimental results showed that compared with non-imprinted polymers (NIPs), MIPs had a larger specific surface area and special pore structure and that different from the Langmuir model of NIPs, the static adsorption isotherm of MIPs for Re was in good agreement with the Freundlich model based on the two adsorption properties of MIPs. The curves of the adsorption dynamics and the lines of kinetic correlation indicate that there was a fast and selective adsorption equilibrium for Re because of the affinity of MIPs to the template rather than its analogue of ginsenoside Rg1 (Rg1). The study of thermodynamics indicate that the adsorption was controlled by enthalpy and that MIPs had higher enthalpy and entropy than NIPs, which contributed to the specific recognition of MIPs.

“…Although puchiin has been reported for a long time, the qualification and quantification of antibacterial activity‐contributing components are still limited. Coupled with advances in analytical techniques, some emerging strategies including high‐speed countercurrent chromatography (HSCCC), 77 molecular imprinting technology (MIT) 78 and centrifugal partition chromatography (CPC) 79 would be helpful in fully elucidating the chemical profile of puchiin.…”

Section: Nutrients and Phytochemicalsmentioning

confidence: 99%

Eleocharis dulcis corm: phytochemicals, health benefits, processing and food products

et al. 2021

J Sci Food Agric

Eleocharis dulcis, an aquatic plant belonging to Cyperaceae family, is indigenous to Asia, and also occurs in tropical Africa and Australia. The edible corm part of E. dulcis is a commonly consumed aquatic vegetable with a planting area of 44.46 × 103 hm2 in China. This work aims to explore the potential of E. dulcis corm for use as a new food source for sufficient nutrients and health benefits by reviewing its nutrients, phytochemicals, functions, processing and food products. Eleocharis dulcis corm contains starches, dietary fibers, non‐starch polysaccharides, proteins, amino acids, phenolics, sterols, puchiin, saponins, minerals and vitamins. Among them, phenolics including flavonoids and quinones could be the major bioconstituents that largely contribute to antioxidant, anti‐inflammatory, antibacterial, antitumor, hepatoprotective, neuroprotective and hypolipidemic functions. Peel wastes of E. dulcis corm tend to be enriched in phenolics to a much higher extent than the edible pulp. Fresh‐cut E. dulcis corm can be consumed as a ready‐to‐eat food or processed into juice for beverage production, and anti‐browning processing is a key to prolonging shelf life. Present food products of E. dulcis corm are centered on various fruit and vegetable beverages, and suffer from single categories and inadequate development. In brief, underutilized E. dulcis corm possesses great potential for use as a new food source for sufficient nutrients and health benefits. © 2021 Society of Chemical Industry.