Preparation and characterization of synthetic melanin-like nanoparticles reinforced chitosan nanocomposite films

Roy, Swarup; Hai, Le Van; Kim, Hyun-Chan; Zhai, Lindong

doi:10.1016/j.carbpol.2019.115729

Cited by 115 publications

(77 citation statements)

References 56 publications

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“…Both increased significantly as melanin content increased. This observation is in line with the findings of other authors who used melanins to modify biopolymer-based films, such as chitosan and agar [14,19]. In contrast, Yang et al [21] noticed that the MC of alginate/poly(vinyl alcohol) films decreased with increased melanin content, similarly as observed by Roy et al for the case of cellulose/melanin films [22].…”

Section: Hydrodynamic Properties (Moisture Content Water Solubility supporting

confidence: 88%

“…The moisture content (MC), water solubility (WS), and swelling ratio (SR) of obtained films were analyzed following the methodology of Roy et al [14]. In brief, MC was determined as the weight change of the films after drying at 105 • C for 24 h. To determine the water solubility (WS), film specimens (2.5 cm × 2.5 cm) were first dried at 60 • C overnight and then weighed.…”

Section: Determination Of Moisture Content Water Solubility and Swelmentioning

confidence: 99%

“…They are typically used to extend the shelf life and/or to improve the quality of foods. For example, they can be used to act as barriers to mass transfer, carriers of specific ingredients, or for the improvement of mechanical/handling characteristics of the product [13][14][15]. Growing consumer demand for high-quality foods, along with increasing environmental concern regarding the disposal of non-renewable food packaging materials, has led to a great deal of interest in the development of novel, biodegradable edible films/coatings [1,15,16].…”

Section: Introductionmentioning

confidence: 99%

“…As a result, there is a pressing need to develop new, more eco-friendly packaging materials. In this context, biopolymers are very promising, because, compared to petroleum-based synthetic plastics, they are derived from a biological origin, making them renewable, biodegradable, and non-toxic or biocompatible [1,14]. A wide range of carbohydrates, proteins, and lipids-all derived from renewable sources-are being investigated as biodegradable alternatives, to improve sustainability and recyclability [1,13,20,21].…”

Section: Introductionmentioning

confidence: 99%

“…However, compared to their potential, the use of melanins remains under-explored. The relatively few examples typically involve their blending/use with polymers (as chemical modifiers or nanofillers) to modify films and coatings, for example: gelatin [38,39], poly(lactic acid) [18], alginate [21], agar [19], carrageenan [13], cellulose [22], chitosan [14], poly(vinyl alcohol) [40], polypropylene/poly(butylene adipate-co-terephthalate) [37], polyhydroxybutyrate [41] and, ethylene-vinyl acetate copolymer [35].…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Whey Protein Concentrate/Isolate Biofunctional Films Modified with Melanin from Watermelon (Citrullus lanatus) Seeds

et al. 2020

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Valorization of food industry waste and plant residues represents an attractive path towards obtaining biodegradable materials and achieving “zero waste” goals. Here, melanin was isolated from watermelon (Citrullus lanatus) seeds and used as a modifier for whey protein concentrate and isolate films (WPC and WPI) at two concentrations (0.1% and 0.5%). The modification with melanin enhanced the ultraviolet (UV) blocking, water vapor barrier, swelling, and mechanical properties of the WPC/WPI films, in addition to affecting the apparent color. The modified WPC/WPI films also exhibited high antioxidant activity, but no cytotoxicity. Overall, the effects were melanin concentration-dependent. Thus, melanin from watermelon seeds can be used as a functional modifier to develop bioactive biopolymer films with good potential to be exploited in food packaging and biomedical applications.

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Section: Hydrodynamic Properties (Moisture Content Water Solubility supporting

confidence: 88%

Section: Determination Of Moisture Content Water Solubility and Swelmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Whey Protein Concentrate/Isolate Biofunctional Films Modified with Melanin from Watermelon (Citrullus lanatus) Seeds

et al. 2020

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Multistimulus‐Responsive Miniature Soft Actuator with Programmable Shape‐Morphing Design for Biomimetic and Biomedical Applications

Nan,

Go,

Song

et al. 2024

Adv Funct Materials

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Miniature soft actuators have garnered attention across healthcare, military, and industrial fields; however, soft actuators mostly have functions and applications in nature‐inspired biomimetic locomotion, without any specific approaches reported for biomedical applications. In biomedical applications, soft actuators must be biodegradable, biocompatible, and visible in vivo. This study presents a multifunctional soft actuator comprising chitosan and magnetic nanoparticles (MNPs) fabricated via facile casting and laser micromachining. The actuator demonstrates programmable shape morphing and responds swiftly to six stimuli: humidity, chemical solvents, near‐infrared (NIR) light, radio‐frequency (RF) heating, temperature, and magnetic fields. This actuator shows feasibility for biomimetic applications, such as flower, leaf, larva, and finger. Furthermore, the actuator demonstrates magnetic locomotion, real‐time X‐ray visibility, biocompatibility, and biodegradability both in vitro and in vivo. The multistimulus‐responsive shape‐morphing performance of the soft actuator has potential as a wireless miniature robot in various fields, including biomimetic and biomedical applications.

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Chitosan/nanocellulose‐based bionanocomposite films for controlled betamethasone and silver sulfadiazine delivery

Riccio

Klosowski

Prestes

et al. 2021

J of Applied Polymer Sci

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Bionanocomposite films based on chitosan and nanocellulose (nanocrystals or nanofibrils) have gained considerable attention for biomedical applications, especially for wound dressings. However, the development of these films as controlled drug release dressings is still under-exploited. Therefore, this work aimed to design chitosan/nanocellulose-based bionanocomposite films, loaded by betamethasone or silver sulfadiazine, as functional dressings. The films were obtained by solvent casting and characterized by physicochemical, mechanical, barrier properties, in vitro drug release, and antimicrobial activity. The nanocellulose type, physical state, and content caused influence on the film's properties providing different physical, barrier, and drug release profiles. They are semi-occlusive and mechanically resistant; the drug release is controlled, and possesses antimicrobial activity. In conclusion, the developed biodegradable bionanocomposite films are promising as active dressings for controlled drug delivery in the wound site and have specific applications according to their features to treat inflamed and purulent wounds, noninfectious dry wounds, and infectious wounds.

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Preparation and characterization of synthetic melanin-like nanoparticles reinforced chitosan nanocomposite films

Cited by 115 publications

References 56 publications

Whey Protein Concentrate/Isolate Biofunctional Films Modified with Melanin from Watermelon (Citrullus lanatus) Seeds

Whey Protein Concentrate/Isolate Biofunctional Films Modified with Melanin from Watermelon (Citrullus lanatus) Seeds

Multistimulus‐Responsive Miniature Soft Actuator with Programmable Shape‐Morphing Design for Biomimetic and Biomedical Applications

Chitosan/nanocellulose‐based bionanocomposite films for controlled betamethasone and silver sulfadiazine delivery

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