Preparation and characterization of poly[acrylamide‐co‐3‐(acryloylamino)propyldodecyldimethylammonium bromide]/polyoxometalate composite microspheres

Abstract

Surfmer [3-(acryloylamino)propyl]dodecyldimethyl ammonium bromide (APDDAB) was synthesized and characterized. On the basis of the reverse emulsion polymerization technique, poly [acrylamide-co-3-(acryloylamino)propyldodecyldimethylammonium bromide] [P(AMco-APDDAB)] copolymer microgels were obtained with the copolymerization of acrylamide and APDDAB. The P(AM-co-APDDAB)/polyoxotungstates composite microspheres were prepared with the ion-exchange reaction of the P(AM-co-APDDAB) microgels with phosphotungstic acid (H 3 PW 12 O 40 ). The morphologies and components of the composite microspheres were characterized by scanning electron microscopy, energy-dispersive X-ray spectroscopy, thermogravimetric analysis, and Fourier transform infrared spectroscopy. The results indicate that the P(AM-co-APDDAB)/PW 12 O 40 composite microspheres all had a core-shell structure. For the composite microspheres, the hydrogel P(AM-co-APDDAB) was dominantly located in the core, and the complexes of PW 12 O 40 3À with APDDAB were mainly located in the surface; these features made the composite microspheres amphiphilic and provided for potential catalysis in a two-phase reaction.

Fabrication of tailorable pH responsive cationic amphiphilic microgels on a microfluidic device for drug release

“…If a comonomer of different hydrophilicity/hydrophobicity is incorporated into the droplet, with the aim to produce microgels with both hydrophilic and hydrophobic moieties, the comonomer will diffuse into the CP with which it is more compatible. Therefore, the synthesis of amphiphilic microgels is challenging and usually requires either postmodifications and/or multistep procedures . A common strategy is the fabrication of hydrophilic microgels followed by their modification via covalently or electrostatically binding amphiphilic or hydrophobic moieties .…”

“…Therefore, the synthesis of amphiphilic microgels is challenging and usually requires either postmodifications and/or multistep procedures . A common strategy is the fabrication of hydrophilic microgels followed by their modification via covalently or electrostatically binding amphiphilic or hydrophobic moieties . However, this results in the synthesis of microgels with a core‐shell structure, where the hydrophobic groups are grafted onto the shell of the microgel structure.…”

“…6,38 A common strategy is the fabrication of hydrophilic microgels followed by their modification via covalently or electrostatically binding amphiphilic or hydrophobic moieties. 1,4,7,[34][35][36][37] However, this results in the synthesis of microgels with a core-shell structure, where the hydrophobic groups are grafted onto the shell of the microgel structure. We are aiming for the fabrication of amphiphilic microgels with different structures, in particular where the hydrophobic and hydrophilic groups are both on the elastic chain, the polymer chain between the cross-links, and not grafted onto the outer surface of the microgel, which can influence the microgel's ability to encapsulate and release drugs.…”

Microfluidically fabricated pH-responsive anionic amphiphilic microgels for drug release

“…Likewise, if the CP is based on oil or an organic solvent, then hydrophobic reagents would diffuse from the droplets to the CP. Thus, amphiphilic microgels are usually prepared using postmodifications 1,4,7,[17][18][19][20][21] and/or multi-step procedures. 6,22 Typically, hydrophilic microgels are initially fabricated and then modified to produce amphiphilic microgels by covalently or electrostatically binding amphiphilic or hydrophobic moieties.…”

Preparation and characterization of supermacroporous polyacrylamide cryogel beads for biotechnological application

“…For example, calcium carbonate is one of the most popular salts used as porogen. Pores are formed by mixing calcium carbonate with precursors of the beads and then removed by the hydrochloric acid …”