Preparation and characterization of novel silk fibroin/2-(N,N-dimethylamino)ethyl methacrylate based composite hydrogels with enhanced mechanical properties for controlled release of cefixime

Acceleration of Wound Healing in Diabetic Rats through Poly Dimethylaminoethyl Acrylate–Hyaluronic Acid Polymeric Hydrogel Impregnated with a Didymocarpus pedicellatus Plant Extract

“…The wide band at 3400 cm −1 originates from the −OH structural polymeric association and from the stretch in the N−H groups of the D. pedicellatus extract. 28,30 Asymmetrical and symmetrical stretching of methyl groups in the pDMAEMA−HA and pDPi-DMAEMA−HA hydrogels were observed as weak vibrations at a range of 2800−3000 cm −1 . 28,31 However, respective peaks of phenolics and flavonoids were found in the range of 1000−1600 cm −1 in the D. pedicellatus extract and present in the pDPi-DMAEMA−HA hydrogel.…”

“…These porous structures facilitate aqueous solution flow into the gel and plays an important role to achieve the pDMAEMA–HA hydrogel to absorb more aqueous solvent. 26 , 28 , 29 The pore size of hydrogel might be increased because of the impregnation of phytochemicals in to the pDPi-DMAEMA–HA. In our previously reported study, pAcD and pMcD hydrogels were found to have a structural framework comprising inter-connected nanogels and continuous outer skin with macroporous interiors as visualized by SEM.…”

“…Hydrogel of pDMAEMA–HA was seen with a large number of open porous structures (∼1 mm), while pDPi-DMAEMA–HA hydrogel was also seen with less numbers of open porous structures (∼1000 nm) and smaller size of particles (400–500 nm). These porous structures facilitate aqueous solution flow into the gel and plays an important role to achieve the pDMAEMA–HA hydrogel to absorb more aqueous solvent. ,, The pore size of hydrogel might be increased because of the impregnation of phytochemicals in to the pDPi-DMAEMA–HA. In our previously reported study, pAcD and pMcD hydrogels were found to have a structural framework comprising inter-connected nanogels and continuous outer skin with macroporous interiors as visualized by SEM …”

Enhanced antimicrobial treatment by a clay-based drug nanocarrier conjugated to a guanidine-rich cell penetrating peptide

“…6 ). 72 For preparation of the samples, 50 mg of VCM@Fe 3 O 4 /HNT–C(WR) 3 and OFX@Fe 3 O 4 /HNT–C(WR) 3 particles were put in two separate flasks, then ultrasonicated in 25 mL of dimethyl sulfoxide (DMSO), for an hour at room temperature. Simultaneously, the same procedure was carried out for a sample of Fe 3 O 4 /HNT–C(WR) 3 particles to provide an appropriate solution for the base line.…”

Property Regulation of Conjugated Oligoelectrolytes with Polyisocyanide to Achieve Efficient Photodynamic Antibacterial Biomimetic Hydrogels

“…Biomimetic antibacterial hydrogels are appealing alternatives in antibiotic-free antibacterial applications such as effective wound treatment because of their good biocompatibility and water dispersibility. − The capability of creating or remaining in a moist environment as well as providing an adhesive-free coverage of underlying tissues, makes hydrogel-based wound dressing to be employed as moist pads for wound healing. ,, The antimicrobial activities of antibiotic-free hydrogels have been continuously developed using strategies such as endowing hydrogels with inherent antimicrobial activity, loading them with antibacterial agents, or building hydrogel platforms with stimuli-triggered antibacterial activity . Recently, biocompatible antimicrobial biomimetic hydrogels with photodynamic and photothermal therapy activity have shown great potential for further clinical applications. ,,, However, one of the limitations of these systems for practical use comes from inadequate antibacterial efficiency and biocompatibility. ,, …”