Preparation and characterization of nano statins using oyster mushroom (Pleurotus sajor-caju): a new strategy to reduce toxicity and enhance efficacy for the treatment of cardiovascular disease

Mehra, Akansha; Narang, Rajiv; Jain, V. K.; Nagpal, Suman

doi:10.1016/j.eujim.2019.101014

Cited by 7 publications

(2 citation statements)

References 19 publications

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“…Singer is in combination with drugs to increase their solubility. Mehra et al [40] used oyster mushroom ( P. sajor-caju [Fr.] Singer) to prepare nanoparticles of statins and investigated whether this led to better solubility.…”

Section: Properties Of Pleurotus Mushroomsmentioning

confidence: 99%

Effects of bioactive compounds from Pleurotus mushrooms on COVID-19 risk factors associated with the cardiovascular system

Reis

Schenkel

Camassola

2022

Journal of Integrative Medicine

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Section: Properties Of Pleurotus Mushroomsmentioning

confidence: 99%

Effects of bioactive compounds from Pleurotus mushrooms on COVID-19 risk factors associated with the cardiovascular system

Reis

Schenkel

Camassola

2022

Journal of Integrative Medicine

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“…Platelet surface molecules can interact with other cells and activate platelet chemokines and cause inflammation, another factor that can cause cardiovascular disease (Khodadi, 2020). Some mushroom extracts and metabolites such as polyphenols, polyketides, terpenes, steroids, and polysaccharides are known for their anti‐inflammatory attributes, making them a potential therapeutic use for cardiovascular disorders (Lee et al., 2019; Mehra et al., 2020).…”

Section: Nutraceutical Potential Of Mushroom Bioactive Metabolitesmentioning

confidence: 99%

Nutraceutical potential of mushroom bioactive metabolites and their food functionality

Ishara

Buzera

Mushagalusa

et al. 2021

Journal of Food Biochemistry

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Numerous mushroom bioactive metabolites, including polysaccharides, eritadenine, lignin, chitosan, mevinolin, and astrakurkurone have been studied in life‐threatening conditions and diseases such as diabetes, cardiovascular, hypertension, cancer, DNA damage, hypercholesterolemia, and obesity attempting to identify natural therapies. These bioactive metabolites have shown potential as antiviral and immune system strengthener natural agents through diverse cellular and physiological pathways modulation with no toxicity evidence, widely available, and inexpensive. In light of the emerging literature, this paper compiles the most recent information describing the molecular mechanisms that underlie the nutraceutical potentials of these mushroom metabolites suggesting their effectiveness if combined with existing drug therapies while discussing the food functionality of mushrooms. The findings raise hope that these mushroom bioactive metabolites may be utilized as natural therapies considering their therapeutic potential while anticipating further research designing clinical trials and developing new drug therapies while encouraging their consumption as a natural adjuvant in preventing and controlling life‐threatening conditions and diseases. Practical applications Diabetes, cardiovascular, hypertension, cancer, DNA damage, hypercholesterolemia, and obesity are among the world's largest life‐threatening conditions and diseases. Several mushroom bioactive compounds, including polysaccharides, eritadenine, lignin, chitosan, mevinolin, and astrakurkurone have been found potential in tackling these diseases through diverse cellular and physiological pathways modulation with no toxicity evidence, suggesting their use as nutraceutical foods in preventing and controlling these life‐threatening conditions and diseases.

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New Trends from Fungi Secondary Metabolism in the Pharmaceutical Industry

Calhelha

Shiraishi

Ribeiro

et al. 2023

Natural Secondary Metabolites

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Preparation and characterization of nano statins using oyster mushroom (Pleurotus sajor-caju): a new strategy to reduce toxicity and enhance efficacy for the treatment of cardiovascular disease

Cited by 7 publications

References 19 publications

Effects of bioactive compounds from Pleurotus mushrooms on COVID-19 risk factors associated with the cardiovascular system

Effects of bioactive compounds from Pleurotus mushrooms on COVID-19 risk factors associated with the cardiovascular system

Nutraceutical potential of mushroom bioactive metabolites and their food functionality

New Trends from Fungi Secondary Metabolism in the Pharmaceutical Industry

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