Preparation and characterization of multifunctional magnetic mesoporous calcium silicate materials

Abstract

We have prepared multifunctional magnetic mesoporous Fe–CaSiO3 materials using triblock copolymer (P123) as a structure-directing agent. The effects of Fe substitution on the mesoporous structure, in vitro bioactivity, magnetic heating ability and drug delivery property of mesoporous CaSiO3 materials were investigated. Mesoporous Fe–CaSiO3 materials had similar mesoporous channels (5–6 nm) with different Fe substitution. When 5 and 10% Fe were substituted for Ca in mesoporous CaSiO3 materials, mesoporous Fe–CaSiO3 materials still showed good apatite-formation ability and had no cytotoxic effect on osteoblast-like MC3T3-E1 cells evaluated by the elution cell culture assay. On the other hand, mesoporous Fe–CaSiO3 materials could generate heat to raise the temperature of the surrounding environment in an alternating magnetic field due to their superparamagnetic property. When we use gentamicin (GS) as a model drug, mesoporous Fe–CaSiO3 materials release GS in a sustained manner. Therefore, magnetic mesoporous Fe–CaSiO3 materials would be a promising multifunctional platform with bone regeneration, local drug delivery and magnetic hyperthermia.

Effects of Mullite, Maghemite, and Silver Nanoparticles Incorporated in β-Wollastonite on Tensile Strength, Magnetism, Bioactivity, and Antimicrobial Activity

“…The prominent peak of maghemite (γ-Fe 2 O 3 ) phase was observed at theta 35°, for mullite at 26.1°, silver (Ag) clearly at 38.2°, and most of the peak of βWMAF was dominant by β-wollastonite phase (β-CaSiO 3 ) at 30°, 50.2°, 53.3°, and 39.1°. Referring to previous reports, amorphous CaSiO 3 has a faster apatite-formation capacity owing to the accelerated release of Ca ions relative to alpha-wollastonite (α-CaSiO 3 ) and beta-wollastonite (β-CaSiO 3 ) [ 46 ]. Consequently, βWMAF materials may enhance bioactivity.…”

“…In this study, apatite formation on the surface of βWMAF was influenced by maghemite and silver. Some researchers also confirmed the use of silver and maghemite as dopant materials [ 46 , 51 , 52 ]. Meanwhile, mullite does not help in apatite formation due to its inert properties in nature [ 51 ].…”

Preparation and characterization of mesoporous calcium‐doped silica‐coated TiO2 scaffolds and their drug releasing behavior

“…Another relevant study was carried out by Zhu et al, who prepared and characterized ordered mesoporous strontium (Sr)‐ substituted CaSiO 3 (Sr‐CaSiO 3 ) materials using P123 as a structure‐directing agent and investigated their drug release properties considering gentamicin as a model drug . In a related investigation, Zhang et al prepared and characterized multifunctional magnetic mesoporous Fe‐CaSiO 3 materials using P123 and they investigated the drug release properties using gentamicin . Moreover, Pei et al fabricated mesoporous calcium silicate/calcium sulfate cement scaffolds by 3D printing technique.…”

Synthesis and characterizations of nanoporous carbon derived from Lapsi (Choerospondias axillaris) seed: Effect of carbonization conditions

“…Porous materials have been significantly developed because of their fundamental properties and potential applications in many research areas including adsorption, storage, separation, and sensing [1][2][3][4][5][6]. Porous materials have been classified according to their pore diameters; micropores are those with diameters less than 2 nm, mesopores range from 2 nm to 50 nm, and macropores are larger than 50 nm in diameter.…”

“…The LSP was mixed with sodium hydroxide (NaOH) in 1:1 wt. ratio and carbonized at 400°C for different time (3,4, and 5 h) and at different temperature (400, 500, 600, and 700°C) for 3 h under a constant flow of ultrapure nitrogen gas. The obtained LSP-derived NACs were carefully characterized and the effect of the conditions during preparation on the structural properties was also investigated.…”