Preparation and characterization of mucilage polysaccharide for biomedical applications

Archana, G.R.; Sabina, K.; Babuskin, S.; Radhakrishnan, K.; Fayidh, Mohammed A.; Babu, Packirisamy Azhagu Saravana; Sivarajan, M.; Sarojadevi, M.

doi:10.1016/j.carbpol.2013.04.062

Cited by 118 publications

(78 citation statements)

References 23 publications

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“…The mucilage polysaccharide exhibited more or less common constant peaks. In the two similar previous works, the bands of okra mucilage were obtained at 3402.5, 2928.0, 2366.9, 2345.4, 1617.6, 1419.9, 1319.9, 1281.3, 1195.9, 1096.1, and 669.6 cm −1 (14) and the bands of Ficus reticulata fruit mucilage were detected at 3155. 3, 2935.5, 2885.3, 2098.4, 1635.5, 1234.4, 1110.9, 991.3, and 852.5 cm −1 (28).…”

Section: Ftir Characterization Of the Productssupporting

confidence: 67%

“…Furthermore, it is known from literature that polymers with hydrophilic groups, such as carboxyl and hydroxyl groups, can strongly bind with the oligosaccharide chains of the mucous layer (14). It was also noted that carboxyl and hydroxyl groups makes this polymer capable to form hydrogen bond.…”

Section: Ftir Characterization Of the Productsmentioning

confidence: 99%

“…Thus, basil seed mucilage has good bioadhesive property singly or in combination with polysaccharides like alginate sulfate for biofilm formation and drug delivery systems. Many actives can be released through such bio adhesives, as steroids, anti-inflammatory agents, pH-sensitive peptides, and small proteins such as insulin, and local treatments to alleviate pain in the buccal cavity (14). From the IR data, it is concluded that those which are rich in protein can form strong gels when lignin is bonded with Ca 2+ ions, Ba 2+ , and Sr 2+ (30) by cross-linking, similar to guar and okra gums.…”

Section: Ftir Characterization Of the Productsmentioning

confidence: 99%

“…They are widely used in the pharmaceutical industries as adjuvant, thickeners, suspending agents, binders, and granulating agent and are also used as matrices for sustained and controlled drug delivery (1,2,(10)(11)(12)(13)(14)(15)(16)(17). Mucilage is a gelatinous substance which when concentrated is called as gum.…”

Section: Introductionmentioning

confidence: 99%

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Supercritical CO2 Generation of Nanometric Structure from Ocimum basilicum Mucilage Prepared for Pharmaceutical Applications

2014

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Abstract. Plant-derived polymers are widely used in the pharmaceutical industry due to their emollient, lack of toxicity, and irritating nature and low cost. In this work, basil seed mucilage was dried using supercritical carbon dioxide phase inversion technique to form a nanometric structure. The obtained polymeric structures were characterized by scanning electron microscopy (SEM), Brunauer-EmmettTeller (BET) method, and Fourier transform infrared spectroscopy (FTIR) and compared with the ovenderived sample group. It was demonstrated that the product morphology could be controlled by altering the composition of methanol which functioned as the co-solvent in the nonsolvent stream. The most homogeneous product (60-nm mean pore size diameter, 78 m 2 /g BET surface area with no agglomeration) was obtained with 2.5% methanol. The FTIR data showed that the presence of hydroxyl and carboxyl groups suggested the bioadhesive property of basil seed mucilage was good and many active pharmaceutical compounds might be loaded to the resultant nanometric structure to enhance drug release. Furthermore, the FTIR analyses indicated that the nature of the final product did not change during the supercritical drying procedure.

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Section: Ftir Characterization Of the Productssupporting

confidence: 67%

Section: Ftir Characterization Of the Productsmentioning

confidence: 99%

Section: Ftir Characterization Of the Productsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Supercritical CO2 Generation of Nanometric Structure from Ocimum basilicum Mucilage Prepared for Pharmaceutical Applications

2014

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“…For this purpose, biodegradable natural polymers such as polysaccharides and protein have been widely used (Younes and Cohn 1987;Jeong et al 1997;Wijesinghe and You-Jin 2012;Archana et al 2013;El-Aassar et al 2013;Moustafa et al 2013).…”

Section: Introductionmentioning

confidence: 99%

Preparation, characterization and antibacterial activity of biodegradable films prepared from carrageenan

El-Fawal

2014

J Food Sci Technol

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Carrageenan films have been formulated as a packaging material. Films plasticized with glycerol were loaded with citric acid (1, 0.75, 0.5, 0.25 and 0.1 %) for enhanced antimicrobial effects. Blank and citric acid loaded films were characterized by mechanical properties, scanning electron microscopy and contact angle. In addition, swelling and antibacterial studies were conducted to further characterize the films. Both blank and citric acid loaded films showed different morphology, high elasticity and acceptable tensile (mechanical) properties. These citric acid loaded films p r o d u c e d h i g h e r z o n e s o f i n h i b i t i o n a g a i n s t Staphylococcus aureus, Proteus mirabilis, Pseudomonas aeruginosa, Escherichia coli and Dickeya chrysanthemi strains compared to blank film.

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Edible films from mucilage of Cereus hildmannianus fruits: Development and characterization

Damas

Pereira

Nishihora

et al. 2017

J of Applied Polymer Sci

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Mucilages are heteropolysaccharides with rich monosaccharide composition. They are capable of forming films that are brittle and fragile, and in order to obtain flexible materials, plasticizers must be added. The present study aims to evaluate the physicochemical properties of mucilage‐based films produced with Cereus hildmannianus and different glycerol concentrations by the casting technique. Transparent and yellowish films were obtained by the addition of glycerol, which also improved handleability, evidenced by increased elongation, and reduced tensile strength and Young's modulus. Thermal gravimetric analysis and differential thermal analysis revealed that glycerol presence reduced the thermal stability, showing the influence of a plasticizer over the polymer structure. Water absorption capacity and contact angle were reduced with the increase of plasticizer concentration; on the other hand, the water vapor permeability increased, as expected, due to the hydrophilic nature of glycerol. The results indicated the potential application of C. hildmannianus mucilage as a promising material to produce edible films. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 45223.

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Preparation and characterization of mucilage polysaccharide for biomedical applications

Cited by 118 publications

References 23 publications

Supercritical CO2 Generation of Nanometric Structure from Ocimum basilicum Mucilage Prepared for Pharmaceutical Applications

Supercritical CO2 Generation of Nanometric Structure from Ocimum basilicum Mucilage Prepared for Pharmaceutical Applications

Preparation, characterization and antibacterial activity of biodegradable films prepared from carrageenan

Edible films from mucilage of Cereus hildmannianus fruits: Development and characterization

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