Preparation and Characterization of Lutein Co-Amorphous Formulation with Enhanced Solubility and Dissolution
Xuening Song,
Yingting Luo,
Wenduo Zhao
et al.
Abstract:Lutein is an oxygenated fat-soluble carotenoid and a functional compound with proven health benefits for the human body. Nevertheless, the poor water solubility and low oral bioavailability of lutein greatly limit its application. To address this, we developed an effective approach to enhance the water solubility of lutein through co-amorphous formulation. Specifically, the lutein-sucralose co-amorphous mixture was prepared at a molar ratio of 1:1 using ethanol and water as solvents by employing the solvent ev… Show more
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