2011
DOI: 10.1002/app.34751
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Preparation and characterization of dual responsive sodium alginate‐g‐poly(vinyl alcohol) hydrogel

Abstract: Poly(vinyl alcohol) (PVA) was chosen as a controllable gelator to prepare sodium alginate (SA)-based physically cross-linked dual-responsive hydrogel by three steps. First, polyvinyl acetate (PVAc) was grafted onto SA via radical copolymerization. Then, the copolymer was subsequently converted into SA-g-poly(vinyl alcohol) (SAPVA) by alcoholysis reaction. PVA content of SAPVA was tailored by controlling the graft percentage of PVAc, i.e. through varying the amount of vinyl acetate during copolymerization. Fina… Show more

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Cited by 20 publications
(5 citation statements)
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“…However, PVA exhibits some unfavorable mechanical properties (e.g. strength and flexibility), as well as a relatively poor thermal stability [210], though this can be improved by blending PVA with other polymers (including naturally based polymers such as chitosan, gelatin, dextran and hyaluronic acid) [211][212][213] or by adequate chemical or physical cross-linking [61,208]. Chemical cross-linking can be obtained by using glutaraldehyde, genipin, succinyl chloride, adipoyl chloride and sebacoyl chloride, while physical cross-linking can be obtained by repeated freeze-thawing cycles [61,209,214].…”
Section: Dfu Dressings Based On Synthetic Polymersmentioning
confidence: 99%
“…However, PVA exhibits some unfavorable mechanical properties (e.g. strength and flexibility), as well as a relatively poor thermal stability [210], though this can be improved by blending PVA with other polymers (including naturally based polymers such as chitosan, gelatin, dextran and hyaluronic acid) [211][212][213] or by adequate chemical or physical cross-linking [61,208]. Chemical cross-linking can be obtained by using glutaraldehyde, genipin, succinyl chloride, adipoyl chloride and sebacoyl chloride, while physical cross-linking can be obtained by repeated freeze-thawing cycles [61,209,214].…”
Section: Dfu Dressings Based On Synthetic Polymersmentioning
confidence: 99%
“…3d1). Generally, PVA is a brittle biomaterial and hence can be combined with other polymers like sodium alginate to confer high stability and mechanical strength [49]. As reported earlier, PVA-alginate hydrogel is a polymeric material with 3D (three-dimensional) networks that possess good elastic properties and [5,23].…”
Section: Biocorrosion Studiesmentioning
confidence: 93%
“…The optimization of the preparation process by using alginate could effectively solve this problem. Sodium alginate has been widely used in hydrogel preparation 36,37 . The sodium ions on the sodium alginate G unit could occur ion‐exchange reactions with multivalent cations, 38 and the gel microspheres can be fabricated by a simple drip method.…”
Section: Introductionmentioning
confidence: 99%