Preparation and characterization of collagen/chitosan composites with silver nanoparticles

Sionkowska, Alina; Walczak, Maciej; Michalska‐Sionkowska, Marta

doi:10.1002/pc.25426

Cited by 24 publications

(27 citation statements)

References 33 publications

(45 reference statements)

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“…Two-component mixtures based on natural polymers have been tested by our group [29][30][31][32][33][34][35][36][37][38][39][40]. Collagen/chitosan mixtures were used to create films and scaffolds [29][30][31][32].…”

Section: Introductionmentioning

confidence: 99%

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Silk Fibroin/Collagen/Chitosan Scaffolds Cross-Linked by a Glyoxal Solution as Biomaterials toward Bone Tissue Regeneration

et al. 2020

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In this study, three-dimensional materials based on blends of silk fibroin (SF), collagen (Coll), and chitosan (CTS) cross-linked by glyoxal solution were prepared and the properties of the new materials were studied. The structure of the composites and the interactions between scaffold components were studied using FTIR spectroscopy. The microstructure was observed using a scanning electron microscope. The following properties of the materials were measured: density and porosity, moisture content, and swelling degree. Mechanical properties of the 3D materials under compression were studied. Additionally, the metabolic activity of MG-63 osteoblast-like cells on materials was examined. It was found that the materials were characterized by a high swelling degree (up to 3000% after 1 h of immersion) and good porosity (in the range of 80–90%), which can be suitable for tissue engineering applications. None of the materials showed cytotoxicity toward MG-63 cells.

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Section: Introductionmentioning

confidence: 99%

“…Materials were characterized by porosity and good mechanical properties. Silk fibroin was mixed with collagen in ratios of 50/50, 25/75, and 75/25 to prepare biopolymer sponges [33][34][35][36]. Furthermore, silk fibroin and chitosan were previously studied by our group [37][38][39][40].…”

Section: Introductionmentioning

confidence: 99%

Silk Fibroin/Collagen/Chitosan Scaffolds Cross-Linked by a Glyoxal Solution as Biomaterials toward Bone Tissue Regeneration

et al. 2020

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“…Hydrogels as biomaterials and their utilization in different biomedical field as various cell and drug delivery vehicles, implants, and so on has been the subject of extensive study over the past decade. [1][2][3][4] Among these, the hydrogels that are formed by in situ polymerization technique have gained popularity as carriers and injectable scaffolds in tissue engineering because of their minimalistic invasive nature of injection and relatively simpler applications. 5,6 A number of hydrophilic polymers have been utilized as primary constituents of hydrogels, some of them being poly (methacrylic acid), 7 poly (N-isopropylacrylamide), 8 poly (acrylamide), 9 poly (ethylene oxide), 10 and poly (2-hydroxyethylmethacrylate).…”

Section: Introductionmentioning

confidence: 99%

Polypropylene oxide/polyethylene oxide‐cellulose hybrid nanocomposite hydrogels as drug delivery vehicle

Prusty

Swain

2020

J of Applied Polymer Sci

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This article deals with the synthesis of hybrid nanocomposite hydrogels through the combination of cellulose (C), polypropylene oxide/poly ethylene oxide (PPO/PEO), and silver nanoparticles (AgNPs) by in situ polymerization technique for the in vitro release of ornidazole drugs. The structure of the resulted materials is identified using SEM, XRD, FTIR, XPS, and TGA spectroscopic techniques. The resulting structure, morphology, thermo responsive property, water retention, and swelling behavior of hydrogels are investigated. The rheological measurement is studied to establish the enhancement of the viscoelasticity and stiffness of hydrogels. The antibacterial activity of the biodegradable silver hybrid nanocomposite hydrogel is investigated by inhibition zone method against gram positive and negative bacteria. Maximum drug release of 96.4% is recorded at 7.4 pH in 5 h. The biocompatibility and cytotoxicity of the hybrid nanocomposite hydrogel are verified using mouse fibroblast cell line L-929 (ATCC CCL-1) cells for their possible use as controlled drug delivery vehicles. The nontoxic nature makes the materials more biocompatible and suitable to apply in the biological systems. Therefore, nontoxic and biocompatible natures of present materials with improved thermal and rheological properties support for their possible uses as drug delivery vehicles.

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“…Collagen is widely used for the preparation of several materials for tissue engineering applications [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 ]. It can be used in several forms, i.e., in the form of a gel, thin films, and a 3D sponge [ 1 , 2 ].…”

Section: Introductionmentioning

confidence: 99%

Modification of Collagen Properties with Ferulic Acid

2020

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Collagen materials are widely used in biomedicine and in cosmetics. However, their properties require improvement for several reasons. In this work, collagen solution as well as collagen films were modified by the addition of ferulic acid (FA). Thin collagen films containing FA were obtained by solvent evaporation. The properties of collagen solution have been studied by steady shear tests. The structure and surface properties of collagen thin films were studied. It was found that for collagen solution with 5% addition of FA, the apparent viscosity was the highest, whereas the collagen solutions with other additions of FA (1%, 2%, and 10%), no significant difference in the apparent viscosity was observed. Thin films prepared from collagen with 1 and 2% FA addition were homogeneous, whereas films with 5% and 10% FA showed irregularity in the surface properties. Mechanical properties, such as maximum tensile strength and elongation at break, were significantly higher for films with 10% FA than for films with smaller amount of FA. Young modulus was similar for films with 1% and 10% FA addition, but bigger than for 2% and 5% of FA in collagen films. The cross-linking of collagen with ferulic acid meant that prepared thin films were elastic with better mechanical properties than collagen films.

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Preparation and characterization of collagen/chitosan composites with silver nanoparticles

Cited by 24 publications

References 33 publications

Silk Fibroin/Collagen/Chitosan Scaffolds Cross-Linked by a Glyoxal Solution as Biomaterials toward Bone Tissue Regeneration

Silk Fibroin/Collagen/Chitosan Scaffolds Cross-Linked by a Glyoxal Solution as Biomaterials toward Bone Tissue Regeneration

Polypropylene oxide/polyethylene oxide‐cellulose hybrid nanocomposite hydrogels as drug delivery vehicle

Modification of Collagen Properties with Ferulic Acid

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