Preparation and characterization of chitosan – collagen peptide / oxidized konjac glucomannan hydrogel

Liu, Liangling; Wen, Huigao; Rao, Ziqie; Zhu, Chen; Li, Meng; Min, Lian; Fan, Lihong; Tao, Shengxiang

doi:10.1016/j.ijbiomac.2017.11.128

Cited by 65 publications

(27 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The peaks became more significant with the increase of oxidation degree. Similar results reported that new absorption peaks around 1730 cm −1 were detected in the oxidized konjac glucomannan by H 2 O 2 [20]. It is known that esters, aldehydes, and carboxylic acids will have C=O stretching peaks around 1715 cm −1 .…”

Section: Resultssupporting

confidence: 81%

Characterization, Antimicrobial Properties and Coatings Application of Gellan Gum Oxidized with Hydrogen Peroxide

Zhao

Fang

2019

Foods

View full text Add to dashboard Cite

The effect of hydrogen peroxide (H2O2) oxidation on the physicochemical, gelation and antimicrobial properties of gellan gum was studied. The oxidized gellan gum (OGG) was characterized by measuring the carboxyl/carbonyl group contents, Fourier transform infrared spectroscopy (FTIR) and proton nuclear magnetic resonance (1H-NMR) spectroscopy. The H2O2 oxidation resulted in a large increase in the carboxyl groups in gellan gum. The OGG lost gelation ability by oxidation even in the presence of metal ions. The antimicrobial activities of the OGG against Gram-positive bacteria (Staphylococcus aureus), Gram-negative bacteria (Escherichia coli), and fungal (Aspergillus niger) were tested. The OGG could inhibit the growth of both bacteria and fungal, and the activity was improved with an increase in the oxidation level. Finally, the application of the OGG as an active coatings material to extend the storage of apples was tested.

show abstract

Section: Resultssupporting

confidence: 81%

Characterization, Antimicrobial Properties and Coatings Application of Gellan Gum Oxidized with Hydrogen Peroxide

Zhao

Fang

2019

Foods

View full text Add to dashboard Cite

show abstract

“…Although collagen and KGM have received extensive focus and explorations for various biomedical purpose [ 38 , 46 , 48 , 49 ], including hybrid films derived from the solution blends of collagen and KGM, the preparation route of combining collagen with KGM in the form of hydrogel from the angle of collagen self-assembly feature to obtain a composite hydrogel with collagen-based hybrid fibrillar networks has rarely been reported so far. This facile synthesis strategy can further broaden and deepen the exploration of the composites of collagen/KGM without just being limited to the form of their hybrid films in biomedical field.…”

Section: Introductionmentioning

confidence: 99%

Construction and evaluation of fibrillar composite hydrogel of collagen/konjac glucomannan for potential biomedical applications

Tang

Chen

Guo

et al. 2018

Regenerative Biomaterials

View full text Add to dashboard Cite

Konjac glucomannan (KGM) is recognized as a safe material for its health-promoting benefits and thus widely used in various fields including pharmaceutical industry. In recent decades, the combination of collagen and KGM attracts more attentions for biomedical purpose, especially the hybrid films of collagen–KGM or collagen–KGM–polysaccharide. In this study, to further and deeply develop the intrinsic values of both collagen and KGM as biomaterials, a novel kind of composite hydrogel comprising collagen and KGM at a certain ratio was fabricated under mild conditions via fibrillogenesis process of the aqueous blends of collagen and KGM that experienced deacetylation simultaneously. The chemical composition, microcosmic architectures, swelling behavior, biodegradation and dynamic mechanic properties of such resulted composite hydrogels were systematically investigated. Biologic experiments, including cell culture in vitro and hypodermic implantation in vivo, were also conducted on these collagen/KGM composite hydrogels to evaluate their biologic performances. The relevant results prove that, based on collagen self-assembly behavior, this synthesis strategy is efficient to construct a composite hydrogel of collagen/KGM with improved mechanical properties, biodegradability, excellent biocompatibility and bioactivity, which are promising for potential biomedical applications such as tissue engineering and regenerative medicine.

show abstract

“…Semipermanent junction points would be formed by the interanchored long chains with enough strength in the polymer network, and the formed networks give an enhancement of the contact and preservation of water molecules . The mount of hydrophilic groups of the polysaccharide varies from a fraction to several thousand times of their own weight when swelled with water . Some functional sections can stabilize the 3D frameworks that allow the interchains conglutinating to avoid dissolution of gels.…”

Section: Fabrication Of Polysaccharide‐based Hydrogelsmentioning

confidence: 99%

Recent Progress of Polysaccharide‐Based Hydrogel Interfaces for Wound Healing and Tissue Engineering

Zhu

Mao

Cheng

et al. 2019

Adv Materials Inter

261

142

View full text Add to dashboard Cite

Polysaccharide is an abundant and reproducible natural material that is biocompatible and biodegradable. Polysaccharide and its derivatives also possess distinctive properties such as hydrophilicity, mechanical stability, as well as tunable functionality. Polysaccharide‐based hydrogels can be constructed via the physical and/or chemical crosslinking of polysaccharide derivatives with different functional molecules, as porous network structures or nanofibrillar structures. This review discusses the biomedical applications of polysaccharide‐based hydrogels containing native polysaccharides, polysaccharide derivatives, and polysaccharide‐composite hydrogels. Recent works on the fabrication, physical properties, advanced engineering, biomedical applications of cellulose‐, chitosan‐, alginate‐, and starch‐based hydrogels are also elaborated. Such porous swelling scaffolds exhibit great advantages at the interface of a negative pressure system such as wound dressing. In addition, the authors also discuss and summarize the exemplary research works of these hydrogels in the applications of drug release, wound dressing, and tissue engineering. Finally, challenges and future perspectives about the development of polysaccharide‐based hydrogels are discussed.

show abstract

Preparation and characterization of chitosan – collagen peptide / oxidized konjac glucomannan hydrogel

Cited by 65 publications

References 40 publications

Characterization, Antimicrobial Properties and Coatings Application of Gellan Gum Oxidized with Hydrogen Peroxide

Characterization, Antimicrobial Properties and Coatings Application of Gellan Gum Oxidized with Hydrogen Peroxide

Construction and evaluation of fibrillar composite hydrogel of collagen/konjac glucomannan for potential biomedical applications

Recent Progress of Polysaccharide‐Based Hydrogel Interfaces for Wound Healing and Tissue Engineering

Contact Info

Product

Resources

About