Preparation and biological evaluation of 99mTc-CO-MIBI as myocardial perfusion imaging agent

An easy and effective method for synthesis and radiolabelling of risedronate as a model for bone imaging

“…The HPLC chromatogram of Re‐risedronate showed one peak at retention time 10.1 min for Re‐risedronate and another beak at 4.2 for ReO 4 − . Technetium complex was washed out with longer retention time than the corresponding rhenium complex, because technetium complex was more hydrophobic than the corresponding rhenium complex, because of the different atomic radii of technetium and rhenium . Similar unmatched retention times have also been observed previously …”

Radioiodination of zearalenone and determination of Lactobacillus plantarum effect of on zearalenone organ distribution: In silico study and preclinical evaluation

“…HPLC analysis revealed a purity for [ 125 I] iodo ZEN up to <99 % after ensuring complete purification Fig. 2 (a, b &c) [ [19] , [20] , [21] , [22] , [23] , [24] , [25] , [26] , [27] , [28] , [29] , [30] , [31] , [32] , [33] , [34] , [35] , [36] , [37] , [38] , [39] , [40] , [41] , [42] , [43] , [44] , [45] , [46] , [47] , [48] , [49] , [50] , [51] , [52] , [53] , [54] , [55] ].

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Radiopharmaceuticals in China: current status and prospects

“…The contrastive imaging of [ 99m Tc(CO) 3 (MIBI) 3 ] + and [ 99m Tc(MIBI) 6 ] + in dog showed better myocardium perfusion imaging achieved by the former complex [35]. Moreover, investigation of different synthetic conditions and the inter-transformation of Tc-CO-MIBI complexes was also performed [36]. In order to explain this phenomenon, the mechanism of the water substitution reactions and the carbonyl ligand exchanges by MIBI was proposed and investigated with Gaussian software [37].…”