Preparation and biological evaluation of radiolabeled-folate embedded superparamagnetic nanoparticles in wild-type rats

Jalilian, Amir Reza; Hosseini-Salekdeh, Seyyedeh Leila; Yousefnia, Hassan; Majdabadi, Abbas; Pouladian, Majid

doi:10.1007/s10967-010-0661-y

Cited by 20 publications

(20 citation statements)

References 16 publications

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“…[8] SPION-folate IR spectrum demonstrated shifted peaks for various functional groups for both starting materials. For instance, folate amide and carboxylic acid groups peaks were all shifted to smaller wave numbers (1447cm -1 ) compared with folic acid (data not shown).…”

Section: Resultsmentioning

confidence: 96%

“…Like SPION-folate synthesis and analysis done in previous work, [8] these processes were reported again including TEM, HRSEM, FT-IR, XRD and VSM tests. Figure 1 shows TEM images of SPION-folate synthesized.…”

Section: Resultsmentioning

confidence: 99%

“…[8] Radiolabeled SPION-folate was prepared by using the procedure mentioned previously with modifications. Briefly, the solution of [ 67 Ga] chloride (1 mCi of [ 67 Ga]-chloride in 0.2M HCl) was evaporated using N 2 gas followed by adding prepared iron salts solution to the [ 67 Ga] vial.…”

Section: Methodsmentioning

confidence: 99%

“…In this study, we have used a different method to produce SPION-folate compared to previous studies. [7][8] Solutions were prepared using deionized (DI) water after 30 min bubbling under an N 2 atmosphere. The iron salts were dissolved in DI water containing 0.5 M HCl where the mole fraction of Fe 2+ to Fe 3+ was adjusted to 1:2 (1 g of FeCl 3 :0.368 g of FeCl 2 ) for all samples.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Evaluation of radiogallium-labeled, folate-embedded superparamagnetic nanoparticles in fibrosarcoma-bearing mice

Hosseini-Salekdeh¹,

Jalilian²,

Yousefnia³

et al. 2012

J Can Res Ther

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Section: Resultsmentioning

confidence: 96%

Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Evaluation of radiogallium-labeled, folate-embedded superparamagnetic nanoparticles in fibrosarcoma-bearing mice

Hosseini-Salekdeh¹,

Jalilian²,

Yousefnia³

et al. 2012

J Can Res Ther

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“…Very recently, SPIONs have been labeled with radiotracers (183,195), hence offering a great opportunity to probe MS with multimodal equipment (e.g., combination of MRI, PET, and SPECT) (85).…”

Section: Spions As Theragnostic Agents For Multiple Sclerosismentioning

confidence: 99%

Superparamagnetic Iron Oxide Nanoparticles: Promises for Diagnosis and Treatment of Multiple Sclerosis

Mahmoudi

Sahraian²,

Shokrgozar

et al. 2011

ACS Chem. Neurosci.

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143

101

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Smart superparamagnetic iron oxide nanoparticles (SPIONs) are the most promising candidate for theragnosis (i.e., diagnosis and treatment) of multiple sclerosis. A deep understanding of the dynamics of the in vivo neuropathology of multiple sclerosis can be achieved by improving the efficiency of various medical techniques (e.g., positron emission tomography and magnetic resonance imaging) using multimodal SPIONs. In this Review, recent advances and challenges in the development of smart SPIONs for theragnostic applications are comprehensively described. In addition, critical outlines of emerging developments are provided from the points of view of both clinicians and nanotechnologists.

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New advances in catalytic performance of erbium‐folic acid‐coated CoFe₂O₄ complexes for green one‐pot three‐component synthesis of pyrano[2,3‐d]pyrimidinone and dihydropyrano[3,2‐c]chromenes compounds in water

Sorkhabi

Mozafari

Ghadermazi

2021

Applied Organom Chemis

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In the current research, much attention is paid to heterogenized nanostructure. Herein, we report the green synthesis magnetic nanoparticles (MNPs) of cobalt ferrite by the immobilization of erbium (Er) coated with folic acid (FA) which show effective catalytic properties and recyclability. Full characterizations with field emission scanning electron microscopy (FE‐SEM), transmission electron microscopy (TEM), energy‐dispersive X‐ray spectroscopy (EDX), X‐ray atomic mapping, thermal gravimetric analysis (TGA), X‐ray diffraction (XRD), vibrating sample magnetometer (VSM), inductively coupled plasma‐optical emission spectrometry (ICP‐OES), and Fourier‐transform infrared (FT‐IR) spectroscopy techniques were undertaken to uncover structural properties of the prepared magnetic catalyst. The obtained nanohybrid complexes as efficient, recyclable, and green heterogeneous systems pave the way for producing pyrano[2,3‐d]pyrimidinone and dihydropyrano[3,2‐c]chromenes derivatives by the one‐pot three‐component condensation reaction of various aldehydes, malononitrile, and hydroxycoumarin or barbituric acid in green condition. This easily prepared organometalic catalyst presents many superiorities such as operational simplicity, high yield, short reaction time, utilization of commercially available or easily accessible starting materials, eco‐friendly properties, and excellent purity. Most importantly, erbium‐FA‐coated CoFe2O4 can be easily separated and recycled from the reaction system using an external magnetic field. The magnetically recoverable biocatalyst can be recycled and reused six times while maintaining high activities. The activity of the magnetic catalyst can be maintained at more than 80% of that of the previous cycle. This research solves the recovery problem encountered in industrial applications of biocatalysts and presents a clean and green method for preparing pyrimidinones and chromenes.

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Preparation and biological evaluation of radiolabeled-folate embedded superparamagnetic nanoparticles in wild-type rats

Cited by 20 publications

References 16 publications

Evaluation of radiogallium-labeled, folate-embedded superparamagnetic nanoparticles in fibrosarcoma-bearing mice

Evaluation of radiogallium-labeled, folate-embedded superparamagnetic nanoparticles in fibrosarcoma-bearing mice

Superparamagnetic Iron Oxide Nanoparticles: Promises for Diagnosis and Treatment of Multiple Sclerosis

New advances in catalytic performance of erbium‐folic acid‐coated CoFe₂O₄ complexes for green one‐pot three‐component synthesis of pyrano[2,3‐d]pyrimidinone and dihydropyrano[3,2‐c]chromenes compounds in water

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Preparation and biological evaluation of radiolabeled-folate embedded superparamagnetic nanoparticles in wild-type rats

Cited by 20 publications

References 16 publications

Evaluation of radiogallium-labeled, folate-embedded superparamagnetic nanoparticles in fibrosarcoma-bearing mice

Evaluation of radiogallium-labeled, folate-embedded superparamagnetic nanoparticles in fibrosarcoma-bearing mice

Superparamagnetic Iron Oxide Nanoparticles: Promises for Diagnosis and Treatment of Multiple Sclerosis

New advances in catalytic performance of erbium‐folic acid‐coated CoFe2O4 complexes for green one‐pot three‐component synthesis of pyrano[2,3‐d]pyrimidinone and dihydropyrano[3,2‐c]chromenes compounds in water

Contact Info

Product

Resources

About

New advances in catalytic performance of erbium‐folic acid‐coated CoFe₂O₄ complexes for green one‐pot three‐component synthesis of pyrano[2,3‐d]pyrimidinone and dihydropyrano[3,2‐c]chromenes compounds in water