Preparation and application of self-assembled systems containing dodecylammonium bromide and chloride as corrosion inhibitors of carbon-steel

“…In the past several decades, the inhibition performances of organic corrosion inhibitors have been investigated sufficiently, and numerous experiments ,,− have shown that inhibition efficiency is largely dependent on inhibitor concentration. These experimental results illustrate that inhibition efficiency first improves significantly with increasing inhibitor concentration.…”

Section: Introductionmentioning

confidence: 99%

How the Inhibition Performance Is Affected by Inhibitor Concentration: A Perspective from Microscopic Adsorption Behavior

Wang

Liu

Wang

et al. 2014

Ind. Eng. Chem. Res.

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In this work, molecular dynamics simulations were employed to investigate the influence of inhibitor concentration on inhibition performance. The adsorption configuration, adsorption process, and inhibition performance were studied. We found that an ordered self-assembled inhibitor film can form on a metal surface, which plays a key role in corrosion inhibition. When the concentration reaches a critical value, inhibitor molecules organize into a micelle in aqueous solution. Further increasing the concentration did not change the inhibitor film on the metal surface, so that the inhibition efficiency remained at a constant level. Our analyses demonstrate that the number of water molecules displaced by inhibitor molecules, the diffusion of water molecules in the inhibitor film, and the stability of the inhibitor film play key roles in the process of corrosion inhibition. This work provides a thorough molecular-level understanding of inhibition behavior and the role of inhibitor concentration.

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“…The mean pH value (4.48 ± 0.10) was within the biologically accepted range for oral administration (2-10), and the refractive index (1.3894 ± 0.0001) showed no statistically significant dif-ference after several repeated measurements. Moreover, the low surface tension value (40.53 ± 1.8 dynes/cm), which can help increase chrysin bioavailability by improving its permeation through the gastrointestinal hydration layer [4], could have been mainly due to the high concentration of non-ionic surfactants used to prepare the microemulsion, which are well known to reduce this physicochemical property at the oil-water interface [36,37]. Finally, when CS-ME was examined with a polarized light microscope, it appeared as a completely dark field (data not shown).…”

Section: Physicochemical Parameters and Polarized Light Microscopymentioning

confidence: 99%

Chrysin-Loaded Microemulsion: Formulation Design, Evaluation and Antihyperalgesic Activity in Mice

et al. 2022

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Chrysin is a bioactive flavonoid found in pollens, passion flowers, honey, royal jelly, and propolis, which is commonly used as an ingredient in natural food supplements and is primarily responsible for their pharmacological properties. A transparent chrysin-loaded microemulsion (CS-ME) prepared through a ternary phase diagram was evaluated for use as an antihyperalgesic formulation. It was formulated with 40% Labrasol® (surfactant), 5% isopropyl myristate (oil phase) and 55% water (aqueous phase) and classified as an oil-in-water (O/W) microsized system (74.4 ± 15.8 nm). Its negative Zeta potential (−16.1 ± 1.9 mV) was confirmed by polarized light microscopy and dynamic light scattering analysis. In vitro studies in Franz-type static diffusion cells showed that chrysin release from CS-ME followed zero-order kinetics. Oral administration of CS-ME in mice resulted in a statistically significantly reduction (p < 0.05) in carrageenan-induced mechanical hyperalgesia compared to the control group. Treatment with CS-ME also showed anti-inflammatory activity by significantly decreasing the TNF-α level (p < 0.01) and increasing that of IL-10 (p < 0.05) compared to the control group. These results suggest that the proposed microsystem is a promising vector for the release of chrysin, being able to improve its capacity to modulate inflammatory and nociceptive responses.

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Preparation and application of self-assembled systems containing dodecylammonium bromide and chloride as corrosion inhibitors of carbon-steel

Cited by 15 publications

References 34 publications

Self-assembling systems based on diquaternized derivatives of 1,4-diazabicyclo[2.2.2]octane

Self-assembling systems based on diquaternized derivatives of 1,4-diazabicyclo[2.2.2]octane

How the Inhibition Performance Is Affected by Inhibitor Concentration: A Perspective from Microscopic Adsorption Behavior

Chrysin-Loaded Microemulsion: Formulation Design, Evaluation and Antihyperalgesic Activity in Mice

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