Preparation and Application of Needle Extraction Device Packed with Sol–gel-Derived Perhydroxy Cucurbit[6]uril Coating Fiber

Polydopamine coated hypodermic needles as a microextraction device for the determination of tricyclic antidepressants in oral fluid by direct infusion MS/MS

“…The sorbent can be coated as a thin lm on the inner surface of the needle [18][19][20] or packed (as particles or monolith) inside it. [21][22][23] In both cases, the technique allows the sample to ow through the needle boosting the interaction with the target analytes. The miniaturized size of the needles requires little solvent for the elution, even when high sample volumes are processed, which is particularly interesting for an efficient preconcentration.…”