Preparation and application of fluorescent monoclonal antibodies recognizing goat CD4+CD25+ regulatory T cells
Yunpeng Wang,
Haoyue Yang,
Jiajin Hu
et al.
Abstract:Regulatory T cells (Tregs) are a subset of T cells participating in a variety of diseases including mycoplasmal pneumonia, contagious ecthyma, and so on. The role of Tregs in goat contagious ecthyma is not completely understood due to the lack of species-specific antibodies. Here, we developed a combination of CD4 and CD25 fluorescence monoclonal antibodies (mAb) to recognize goat Tregs and assessed its utility in flow cytometry, immunofluorescence staining. Using immunofluorescence staining, we found that the… Show more
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