Preparation and antibacterial effect of silver–hydroxyapatite/titania nanocomposite thin film on titanium

Antimicrobial activity of hemocompatible silver doped hydroxyapatite nanoparticles synthesized by modified sol–gel technique

“…It was observed that 3 % Ag-HAp exhibited maximum activity as compared to 1 and 5 % Ag-HAp for both the test organisms. Antimicrobial activity of Ag-HAp based compounds such as plasma sprayed silver containing HAp coatings on Ti plates (Chen et al 2008), magnetron co-sputtered silver containing HAp coatings (Chen et al 2006), Ag-nHAp/TiO 2 /PA66 scaffolds (Xia et al 2010), silver-hydroxyapatite/titania film on titanium plates (Mo et al 2008) and HAp self assembled calcium phosphate glasses (Simon et al 2008) has been attributed to the Ag ions released into the medium. It is well known that silver ions and silver based compounds can destroy cell membranes and cell walls of bacteria and affect their growth (Woo et al 2008;Furr et al 1994).…”

“…(Woo et al 2008;Furr et al 1994;Schreus and Rosenberg 1982;Feng et al 2000) Thus, it has recently become one of the preferred ions to confer microbial resiliency on biomaterials and medical devices (Gristina and Costerton 1985). Several in vitro studies have reported that silver ions in HAp play an important role in preventing or minimizing initial bacterial adhesions (Mo et al 2008;Chen et al 2008).…”

Preparation and characterization of chitosan-silver/hydroxyapatite composite coatings onTiO2 nanotube for biomedical applications

“…Ag inhibits electron transport chain of the bacteria cell, resulting in bacterial destruction [4,5]. It has been incorporated into a variety organic materials [6,7]. Ciobanu et al found the Ag-HAp composite nanoparticles are effective in protecting macrophages from LPS induced cytotoxin in RAW 264.7 macrophage [8].…”

Spontaneous adsorption of silver nanoparticles on Ti/TiO2 surfaces. Antibacterial effect on Pseudomonas aeruginosa

“…Several strategies have been used for their preparation, including the complexation of Ag + ions with mercaptan-terminated phosphonates [41], silver sputtering [38], adsorption of nanoparticles on amine-terminated silane monolayers [42], the use of silver and hydroxyapatite/TiO 2 slurries [43], and sol-gel procedures [40,44], among others. It has been reported that these modified surfaces are biologically compatible [37,45] and present antimicrobial activity [46].…”