Preparation and Antibacterial Activity of Copper and Cobalt Complexes of 4-Chloro-3-nitrobenzoate with a Nitrogen Donor Ligand

Characterization of some amino acid derivatives of benzoyl isothiocyanate: Crystal structures and theoretical prediction of their reactivity

“…)), 7.93 (d, 2H, C(12)eH, and C(16)e H), 7.64 (m, 1H, C(14)eH), 7.52 (m, 2H, C(13)eH and C(15)eH), 4.85 ((q, 1H, C(3)eH), 1.49 (d, 3H, C(5)eH). 13 C NMR (ppm): 13 C NMR (ppm): 179.9 (C(2)eS(1)), 172.9 (C(4)eO(3)), 168.5 (C(1)e(O1)), 133.0C (11), 132.1C (14), 128.7 (C(12) and C(16), 128.4 (C(13) and C(15)), 63.1 (C(3)eH), 17 …”

“…A methoxy substituted derivative of benzoyl isothiocyanate has been accessed by boiling the thione directly in methanol [13]. N-[Benzoylamino)thioxomethyl]amino acid derivatives have been prepared by the reaction of benzoyl isothiocyanate with various amino acids in acetone, namely, histidine, alanine, phenylalanine, serine and cysteine, however the alanine and serine derivatives were characterised by NMR only [14]. The cadmium(II) and zinc(II) complexes of the phenylalanine derivatives have also been reported and characterized by IR, NMR, and microanalysis [14].…”

“…N-[Benzoylamino)thioxomethyl]amino acid derivatives have been prepared by the reaction of benzoyl isothiocyanate with various amino acids in acetone, namely, histidine, alanine, phenylalanine, serine and cysteine, however the alanine and serine derivatives were characterised by NMR only [14]. The cadmium(II) and zinc(II) complexes of the phenylalanine derivatives have also been reported and characterized by IR, NMR, and microanalysis [14]. The cobalt(II), copper(II) and nickel(II) complexes of the aspartic acid, glutamic acid, methionine, leucine and tryptophan derivatives of benzoyl isothiocyanates have been synthesized and tested for their antibacterial activity [15].…”

Investigation of antibacterial activity and related mechanism of a ruthenium(II) polypyridyl complex

“…The appearance of bacterial strains with broad antibiotic resistance is becoming an alarming global health concern. Especially in recent years, microorganisms resistant to antimicrobial agents are serious problems worldwide in the fight against infectious diseases and the development of materials with the ability to inhibit bacterial growth has been of great interest in recent years due to their potential use in everyday products like paints, kitchenware, school and hospital utensils [3]. In the search for drugs with improved clinical effectiveness, reduced toxicity and a broader spectrum of activity, other metals than platinum have been considered, such as Ru, Rh, Cu, Cd and Au [4][5][6][7][8][9].…”

Synthesis, crystal structure, antibacterial activity and theoretical studies on a novel mononuclear cobalt(II) complex based on 2,4,6-tris(2-pyridyl)-1,3,5-triazine ligand

“…However, the development of transition metal complexes as drugs is not an easy task; considerable effort is required to obtain a compound of interest. In general, the ultimate goal is to offer appropriate and efficient antibacterial drugs to patients [4]. Potential metal-antibiotic drugs were focused in line with application of bio-coordination chemistry which appears to be crucial for improving the design of compounds to reduce toxic side effects and understand their mechanisms of action.…”