“…Two-dimensional, three- dimensional and Doppler transthoracic and transoesophageal echocardiography are the first-line imaging modalities for the diagnostic and prognostic assessment of valvular heart disease (VHD), followed by cardiac magnetic resonance for tissue and flow characterization and the detection of myocardial and papillary muscle fibrosis [ 17 , 18 , 19 , 20 , 21 , 22 ]. Moreover, novel data have been reported on computed tomography and positron emission tomography utilizing 18F-fluorodeoxyglucose as a tool for providing evidence of early myocardial inflammation [ 17 , 18 , 19 , 20 , 21 , 22 ]. The introduction of other imaging modalities in the diagnosis of VHD could significantly improve our knowledge concerning cardiac mechanics; the tissue characterization of the burden imposed by the myocardium, calcium and inflammation on valves; and their impact on the severity, progression and prognosis of VHD, not only in symptomatic, but also in asymptomatic patients [ 17 , 18 , 19 , 20 , 21 , 22 ].…”