Preoperative Six-Minute-Walk Test in Lung Transplantation: survival predictor

Caires, Nídia; Silva, Sara Campos; Caldeira, Vânia; Gerardo, Rita; Murinello, Nicole; Santos, Ana Sofia; Borba, Alexandra; Reis, Janildo Ludolf; Calvinho, Paulo; Bravio, Ivan; Martelo, Fernando; Cardoso, João; Semedo, Luísa; Fragata, José

doi:10.1183/1393003.congress-2017.pa1549

Cited by 2 publications

(4 citation statements)

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“…[66][67][68][69][70][71][72][73][74][75][76][77][78][79] Of those, 7 studies showed a significant relationship with mortality posttransplant. [66][67][68][69][70][71][72] Three studies examined the relationship of posttransplant 6MWT with mortality or survival posttransplant 68,80,81 with 2 studies showing a significant relationship with this outcome. 68,80 The relationship of the CPET with mortality posttransplant was examined in 2 studies, 82,83 in which both have shown a significant relationship.…”

Section: Relationship With Clinical Outcomes In Lung Transplant Recip...mentioning

confidence: 99%

“…Fourteen studies examined the relationship of pretransplant 6MWT with mortality posttransplant. [66][67][68][69][70][71][72][73][74][75][76][77][78][79] Of those, 7 studies showed a significant relationship with mortality posttransplant. [66][67][68][69][70][71][72] Three studies examined the relationship of posttransplant 6MWT with mortality or survival posttransplant 68,80,81 with 2 studies showing a significant relationship with this outcome.…”

Section: Relationship With Clinical Outcomes In Lung Transplant Recip...mentioning

confidence: 99%

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Relationship of Exercise Capacity, Physical Function, and Frailty Measures With Clinical Outcomes and Healthcare Utilization in Lung Transplantation: A Scoping Review

Bourgeois

Shallwani

Al-Huda

et al. 2022

Transplantation Direct

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Background. Measures of exercise capacity, frailty, and physical function are commonly used in lung transplant candidates and recipients to evaluate their physical limitations and the effects of exercise training and to select candidates for transplantation. It is unclear how these measures are related to clinical outcomes and healthcare utilization before and after lung transplantation. The purpose of this scoping review was to describe how measures of exercise capacity, physical function, and frailty are related to pre- and posttransplant outcomes. Methods. We considered studies of any design that included performance-based tests of exercise capacity, physical function, and frailty in adult lung transplant candidates or recipients. Outcomes of interest were clinical outcomes (eg, mortality, quality of life) and healthcare utilization. Results. Seventy-two articles met the inclusion criteria. The 6-min walk test (6MWT) was shown to be related to mortality on the waiting list with different distance values as cutoffs points. There were inconsistent results regarding the relationship of the 6MWT with other clinical outcomes. Few studies have examined the relationship between the cardiopulmonary exercise test or the short physical performance battery and clinical outcomes, although some studies have shown relationship with survival posttransplant and quality of life. Few studies examined the relationship between the tests of interest and healthcare utilization‚ and the results were inconsistent. Conclusions. Except for the relationship between the 6MWT and mortality on the waiting list, there is limited evidence regarding the relationship of performance-based measures of exercise capacity, frailty, and physical function with clinical outcomes or healthcare utilization.

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Section: Relationship With Clinical Outcomes In Lung Transplant Recip...mentioning

confidence: 99%

Section: Relationship With Clinical Outcomes In Lung Transplant Recip...mentioning

confidence: 99%

Relationship of Exercise Capacity, Physical Function, and Frailty Measures With Clinical Outcomes and Healthcare Utilization in Lung Transplantation: A Scoping Review

Bourgeois

Shallwani

Al-Huda

et al. 2022

Transplantation Direct

View full text Add to dashboard Cite

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“…1,2 The 6MWT is also used to assess eligibility for surgery including lung transplantation. 3 In pulmonary rehabilitation (PR), the 6MWD is used to prescribe exercise training intensity and to assess changes in functional walking capacity. 2 Because of its association with longer-term outcomes and responsiveness to change, the 6MWD is a commonly used outcome for clinical trials.…”

mentioning

confidence: 99%

“…The 6-min walk distance (6MWD) is a predictor of morbidity and mortality for people with chronic respiratory and cardiovascular conditions, with a shorter 6MWD associated with increased risk of hospitalization and mortality 1,2. The 6MWT is also used to assess eligibility for surgery including lung transplantation 3. In pulmonary rehabilitation (PR), the 6MWD is used to prescribe exercise training intensity and to assess changes in functional walking capacity 2.…”

mentioning

confidence: 99%

Impact of Test Instructions on 6-min Walk Distance in Adults With Chronic Respiratory Disease

Mellerick,

Burge,

Hill

et al. 2023

Journal of Cardiopulmonary Rehabilitation and Prevention

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Purpose: The 6-min walk test (6MWT) is commonly used to assess functional exercise capacity in people with chronic respiratory disease in both clinical and research settings. However, two tests are required to achieve accurate results, due to a well-documented learning effect for the 6-min walk distance (6MWD). Whether it is possible to reduce or eliminate the learning effect by optimizing 6MWT instructions is not known. Methods: People with chronic respiratory disease referred to pulmonary rehabilitation undertook two 6MWT with random allocation to modified instructions (fast—walk as fast as possible; n = 46) or usual instructions (far—walk as far as possible; n = 49). The primary outcome was the learning effect, defined as the difference in the 6MWD between test one and test two. Subgroup analyses investigated whether effects varied in those who were naïve to the 6MWT or according to diagnosis (chronic obstructive pulmonary disease, interstitial lung disease, and bronchiectasis). Results: A learning effect was present in both groups, with a mean improvement in the 6MWD on the second test of 14 m in the fast (modified) group (95% CI, 6-22) and 11 m in the far (usual) group (95% CI, 4-19). There was no statistically or clinically significant difference between groups in the magnitude of the learning effect (between-group difference −3 m, 95% CI, −14 to 8). There was no significant effect of naivety to the 6MWT or diagnosis. Conclusion: The current recommended procedures for the 6MWT, including standardized instructions and performance of two tests on each occasion, should be retained.

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Preoperative Six-Minute-Walk Test in Lung Transplantation: survival predictor

Cited by 2 publications

References 0 publications

Relationship of Exercise Capacity, Physical Function, and Frailty Measures With Clinical Outcomes and Healthcare Utilization in Lung Transplantation: A Scoping Review

Relationship of Exercise Capacity, Physical Function, and Frailty Measures With Clinical Outcomes and Healthcare Utilization in Lung Transplantation: A Scoping Review

Impact of Test Instructions on 6-min Walk Distance in Adults With Chronic Respiratory Disease

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