Preoperative evaluation and predictive value of fine-needle aspiration and frozen section of thyroid nodules

Boyd, Loretta A; Earnhardt, Richard C.; Dunn, John T.; Frierson, Henry F.; Hanks, John B.

doi:10.1016/s1072-7515(98)00221-x

Cited by 93 publications

(84 citation statements)

References 14 publications

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“…Similar conclusion was made in studies done by Charu Batra et al [1], Fatma Althoubaity [2]. However, study by Boyd L.A et al showed no significant difference in sensi vity, specificity or accuracy between FS and FNA [25].…”

Section: Discussionsupporting

confidence: 87%

“…Few authors included deferred category of FS in benign group, and suspicious category in benign group in FNAC [25]. In the present series, for sta s cal evalua on, deferred category was excluded from FS.…”

Section: Discussionmentioning

confidence: 88%

“…The accuracy of FNAC in detec ng cancer is well documented in literature. Boyd LA et alb [25] suggested that FS adds very li le to intraopera ve decision making in pa ents diagnosed as cancer by FNAC. However, Chow et al concluded FS is indicated if preopera ve FNAC suggested malignancy in order to determine the extent of opera on [26] and to avoid surgical over treatment.…”

Section: Discussionmentioning

confidence: 99%

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Accuracy and Diagnostic Utility of Frozen Section in Thyroid Lesions: A Comparative Study

Mushinam¹,

Padua²

2017

IJCBR

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Section: Discussionsupporting

confidence: 87%

Section: Discussionmentioning

confidence: 88%

Section: Discussionmentioning

confidence: 99%

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Accuracy and Diagnostic Utility of Frozen Section in Thyroid Lesions: A Comparative Study

Mushinam¹,

Padua²

2017

IJCBR

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“…The reported pitfalls are those related to specimen adequacy, sampling techniques, the skill of the physician performing the aspiration, the experience of the pathologist interpreting the aspirate and overlapping cytological features between benign and malignant follicular neoplasm. [7][8][9] This study aims correlating the cytological diagnosis with the final histopathological diagnosis to evaluate the sensitivity, specificity and predictive values of positive smears, thereby to assess its role in preoperative diagnosis and planning of proper management of Thyroid swellings. Int J Med Res Prof.2016; 2(3); 204-09.…”

Section: Introductionmentioning

confidence: 99%

Usefulness of Preoperative FNAC of Thyroid Swelling Along with Application of Bethesda System of Reporting

Kasliwal¹,

Tanwar²,

Pachori³

et al. 2016

IJMRP

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Introduction: Fine needle aspiration cytology (FNAC) is the commonly used test for diagnosis of thyroid swellings. FNAC is a cost-effective procedure that provides specific diagnosis rapidly with minimal complications. Based on the cytology findings, patients can be subjected to surgery, thereby decreasing the rate of surgery and its consequent complications. Aims and Objective: Study is aimed to accuracy of FNAC in thyroid as compare with histopathology and classify various cytomorphological lesions of thyroid according to The Bethesda System for Reporting of Thyroid Cytopathology (TBSRTC). Material and Methods: This prospective study was done at our department from January 2013 to June 2015. Total 411 cases presented with thyroid swelling were subjected to thyroid fine needle aspiration cytology (FNAC) and the smears were made followed by routine staining and reporting. The categorization according to the Bethesda system of reporting thyroid cytology was done. The cytological diagnosis was correlated with the histological diagnosis wherever it was available. The accuracy of FNAC for the diagnosis of nonneoplastic and neoplastic lesions was determined using histopathology as the gold standard. Results: Out of total 411 cases, 387 (94.16%) were benign, 15 (3.52%) were Follicular neoplasm, 7(1.70%) cases were malignant and 2 (0.48%) were inadequate. Most frequently encountered lesion was colloid goitre in 217 (52.79%) cases

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“…11 Most studies show accuracy rate exceeding 80%. [12][13][14] Its limitation includes false negative, false positive, indeterminate or suspicious results. 15 The false negative is defined as the patients in which FNAC shows benign pathology but histopathology reveals malignancy 16 , while false positive indicates malignancy in FNAC but histopathology shows benign pathology.…”

Section: Introduction:-mentioning

confidence: 99%

Study of Correlation of Fine Needle Aspiration Cytology With Histopathology in the Diagnosis of Solitary Thyroid Nodule: Our Experience.

Gull¹,

Nisar²,

Jeelani³

et al. 2017

IJAR

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Background: Thyroid nodules are common,thyroid cancer is uncommon and the most common way for it to present is as a solitary thyroid nodule. FNAC has high sensitivity in picking up malignancy in thyroid. The main aim of FNAC is to identify nodules that require surgery and those benign nodules that can be observed clinically and decrease the overall thyroidectomy rate in patients with benign diseases. Objective: To Correlate The FNAC Findings With Histopathology So That Rate Of Unnecessary Thyoidectomies In Benign Pathologies Should Be Avoided. Method: This is a prospective analysis of sixty eight consecutive patients of clinically diagnosed solitary thyroid nodule . All patients who were referred to our department were evaluated. Pre-operative FNAC results were compared with final histopathological diagnosis in all 68 patients. Results: 38 cases were diagnosed as colloid nodular goitre and benign cystic lesions by FNAC. 34 of these cases were nonneoplastic lesions, 2 as papillary carcinoma and 2 as follicular adenoma in histopathological examination . 30 cases were diagnosed as neoplastic lesions (follicular neoplasm, hurthle cell lesions, papillary carcinoma, and suspected malignancy) by FNAC. Statistical analysis of neoplastic lesions showed sensitivity, specificity, false positive rate, false negative rate, positive predictive value, and negative predictive value of FNAC to be 85.7%, 85%, 15%, 14.3%, 85.7%, and 85%, respectively .A total of 12 cases of solitary thyroid nodules were diagnosed as having malignant and the most common malignant lesion detected was papillary carcinoma, 8 out of 12 (66.66%). Conclusion:We concluded that FNAC diagnosis of malignancy is highly significant and such patients should be subjected to surgery. A benign FNAC diagnosis should be viewed with caution as false negative results do occur and these patients should be followed up and any clinical suspicion of malignancy even in the presence of benign FNAC requires surgery.

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Preoperative evaluation and predictive value of fine-needle aspiration and frozen section of thyroid nodules

Cited by 93 publications

References 14 publications

Accuracy and Diagnostic Utility of Frozen Section in Thyroid Lesions: A Comparative Study

Accuracy and Diagnostic Utility of Frozen Section in Thyroid Lesions: A Comparative Study

Usefulness of Preoperative FNAC of Thyroid Swelling Along with Application of Bethesda System of Reporting

Study of Correlation of Fine Needle Aspiration Cytology With Histopathology in the Diagnosis of Solitary Thyroid Nodule: Our Experience.

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