Preoperative depression and mortality in coronary artery bypass surgery: Preliminary findings

Abstract

Elevated depressive symptoms before coronary bypass surgery may be a significant predictor of late death. Prospective studies evaluating the prevalence of depressive symptoms in cardiac surgical patients and their effect on long-term outcome must be undertaken.

Risk factors of depressive and anxiety symptoms 8 years after coronary artery bypass grafting

“…Depressive manifestations occurring in CABG patients at admission constitute the factor of poor prognosis regarding both worsening of physical and psychological functions and the decrease of the quality-of-life scores [4][5][6][7]. They take place even when the result of surgical treatment is satisfactory [2,8,9].…”

Patients with Depression are at Increased Risk for Secondary Cardiovascular Events after Lower Extremity Revascularization

“…Depression is common among patients with coronary heart disease [1][2][3][4] and peripheral arterial disease (PAD). [5][6][7] For patients with acute coronary syndromes, depression is a risk factor for recurrent cardiovascular events and mortality.…”

“…[8][9][10] After coronary artery bypass surgery, it is associated with increased risk for recurrent cardiovascular events, 4,11 rehospitalization for cardiac events, 12 repeat coronary revascularization, 4 and death. 3,13,14 For patients with symptomatic PAD, we have previously described an association between depression and worse outcomes in the revascularized leg. 5 By multivariate analysis, patients with depression at the time of PAD revascularization were at increased risk for recurrent symptomatic PAD in the treated leg and failure of revascularization.…”

Perioperative Anxiety

“…They are preoccupied with discomfort or concerned about the success of surgery, fear of failure of career, postoperative state of physical health and problems adapting to the changed situation. The consequences of perioperative anxiety are major cardiac events [11][12][13] (acute myocardial infarction, heart failure, pulmonary edema), high readmission rate (1 st six month or one years), [11,14] poor quality of life and high rate of cardiac mortality. Impact of perioperative anxiety correlate with high postoperative pain, increased analgesic and anesthetic consumption, prolonged hospital stay, adverse effects on anesthetic induction and recovery, and reduction in patient satisfaction.…”