Preoperative Correction of Water-Electrolyte Disturbances in Patients With Acute Intestinal Obstruction Caused by Colon Cancer

Abstract

Comparative evaluation of preoperative infusion therapy in 50 patients with acute intestinal obstruction of tumour genesis has been performed and parameters of central hemodynamic and water sectors of organism were studied. The patients had a statistically significant reduction of extracellular sector, hypokalaemia, hypornatremia. Central hemodynamic parameters were characterized by a significant reduction in stroke volume and heart rate increase. Mean arterial pressure and peripheral vascular resistance, resistivity reduced in comparison with control group. The study showed that infusion therapy, which includes a balanced colloid solution (HES 130/ 04) and a balanced 700 ml and 1700 ml (average) crystalloid solution and is conducted for 3 hours reduces the severity of water-electrolyte and hemodynamic changes, reduces the need in vasopressor support, and to a certain extent improves outcomes of surgical treatment.