Preoperative C-reactive protein and outcome after coronary artery bypass surgery

Trimetazidina e resposta inflamatória em cirurgia de revascularização do miocárdio

“…This draws attention to studies relating high pre-operative levels of inflammatory markers to post-operative complications, suggesting that those levels should be normal prior to surgery 12,13 .…”

Proteína C Reativa pré-operatória prediz infecção respiratória após cirurgia de revascularização miocárdica

“…In a study with 764 patients undergoing CABG, Biancari et al 13 showed that a value of hsCRP 10 mg/L or more was an independent risk factor for in-hospital mortality, mainly due to cardiac complications. This study poses the question about whether hsCRP is only a marker of severity or may represent a potential target to optimize the preoperative conditions of patients 13 . Another study by the group of Biancari, with 843 patients, evaluated the association of hsCRP levels with longterm post-CABG outcomes.…”

“…Some studies have shown that increased preoperative levels of hsCRP are associated with adverse events after coronary artery bypass graft surgery [13][14][15][16] , whereas others do not find such association 17 . The main complications in the early postoperative period which are directly associated with increased preoperative levels of hsCRP are not clearly known.…”

Is C-Reactive Protein a Predictor of Perioperative Events Before Coronary Artery Bypass?

“…However, until now, studies of the predictive value of CRP have been limited to on-pump CABG. [3][4][5][6] In the past decade, off-pump CABG, which can reduce the systemic inflammatory response caused by cardiopulmonary bypass, has become popular, but there is little data about the relationship of preoperative CRP and the outcome of off-pump CABG.…”