Preoperative autologous blood donation for kidney transplant and end-stage renal disease patients: A single-center study

Kobayashi, Hirohito; Konno, Mayumi; Utsugisawa, Taiju; Tanabe, Kazunari; Kanno, Hitoshi

doi:10.1016/j.transci.2021.103149

Cited by 2 publications

(1 citation statement)

References 30 publications

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“…The chronicity of the anaemia causes a right shift of the oxyhaemoglobin dissociation curve (increased 2,3‐diphosphoglycerate) that improves oxygen unloading, and partially compensates for the anaemia 13 . The value of preoperative transfusion has been questioned and, in fact, abandoned in many human transplant centres due to the risk for antibody‐mediated rejection resulting in graft failure 14 . However, blood product administration may be indicated in some circumstances when patients demonstrate clinical signs associated with anaemia or when anaemia is severe enough to cause increased risk should any additional blood loss occur during surgery.…”

Section: Discussionmentioning

confidence: 99%

Peri‐anaesthetic management of three dogs undergoing renal transplantation surgery

Wilson¹,

Douglas

Aronson

2022

Vet Record Case Reports

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This report describes the perioperative anaesthetic management of three dogs undergoing renal transplant surgery at the University of Pennsylvania using a familial donor kidney. All three cases were pre-medicated with morphine for preoperative sedation and analgesia. Two cases were induced with a combination of fentanyl, midazolam and propofol. One case was induced with etomidate and midazolam. Anaesthesia was maintained with isoflurane in oxygen and an opioid constant-rate infusion in all three cases, with one case also receiving a ketamine constant-rate infusion throughout the anaesthetic procedure. Intraoperative complications that were corrected included hypotension (N = 2), hypokalaemia (N = 2), hyperkalaemia (N = 2), metabolic and respiratory acidosis (N = 2), low colloid-oncotic pressure (N = 2), tachycardia (N = 1), bradycardia (N = 1) and anaemia secondary to intraoperative haemorrhage (N = 1). All dogs survived to be discharged from the hospital. The total survival times were 623, 350 and 46 days, which are longer than the previously reported median survival time of 24 days from discharge.

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Section: Discussionmentioning

confidence: 99%