Preoperative Assessment of Cutaneous Melanoma Thickness Using 10-MHz Sonography

Abstract

In our series of 54 melanomas, 10-MHz sonography measured lesion thickness with good accuracy compared with histopathology. Sonography was effective in discriminating between tumors < or = 1 mm thick and those > 1 mm thick.

High-resolution ultrasound (18-, 22 Mhz) use in the measurement of in vivo thickness of melanoma malignum

“…Az ultrahanggal -szövettani Breslow értékhez képest -alulbecsült esetek hátterében elsôsorban a transducer okozta kompresszió (3,4), valamint az apró-, ultrahanggal nem detektálható sejtfészkek állhatnak (5). A túlbe-csült tumorvastagság hátterében, az esetek jelentôs ré-szében fôként a tumort övezô kereksejtes beszûrôdés (6,7,8), neovascularizáció (2), valamint felszíni hyperkeratosis (3), ulceráció, regressziós jelenségek (9), naevusból kiinduló esetekben a naevusvastagság (2,8), valamint a tumor kimetszésével járó-, a szövettani minta fixálása-kor létrejövô zsugorodás, dehidráció állhat (5,7,8,9,10).…”

Sonography of the Primary Cutaneous Melanoma: A Review

“…On the other hand, using multichanneled color Doppler ultrasound equipment with variable frequency probes that go from 10 to 15 MHz, it has already been reported that ultrasound is capable of differentiating melanomas measuring < or >1 mm of thickness, which is important for requiring, for example, a sentinel lymph node procedure that is indicated in melanomas measuring more than 1 mm thick [13, 14]. …”

Assessment of Tumor Thickness in Melanocytic Skin Lesions: Comparison of Optical Coherence Tomography, 20-MHz Ultrasound and Histopathology

“…Besides the clinical (naked-eye) diagnosis of pigmented lesions there are several noninvasive imaging modalities for evaluation of skin morphology available today [1,2,3,4,5,6,7,8,9,10,11]. Among them, high-frequency ultrasound (HFUS) working with frequencies between 20 and 50 MHz plays the main role in European countries [1,2,3,4,5,6,7]. Although melanomas as well as benign melanocytic nevi cannot be distinguished via ultrasound (both appear as solid homogenous hypoechoic lesions), prior studies have clearly indicated the usefulness of HFUS for determination of the in vivo vertical thickness, volume, and vascularity of melanocytic skin tumors [1,2,3,4].…”

“…Among them, high-frequency ultrasound (HFUS) working with frequencies between 20 and 50 MHz plays the main role in European countries [1,2,3,4,5,6,7]. Although melanomas as well as benign melanocytic nevi cannot be distinguished via ultrasound (both appear as solid homogenous hypoechoic lesions), prior studies have clearly indicated the usefulness of HFUS for determination of the in vivo vertical thickness, volume, and vascularity of melanocytic skin tumors [1,2,3,4]. Optical coherence tomography (OCT) is a relatively new and promising imaging tool which works analogous to ultrasound imaging, except that it uses light rather than sound waves.…”